Human recombinant Clec4G (from HEK293 cells)
Catalog # PRSI96-189
Supplier: ProSci Inc.
CAS Number:
Specifications
- Pk:50 µG
- Protein/peptide type:Recombinant
- Source:HEK293 cells
- Species:Human
- Environmentally Preferable:
- Protein synonyms:CLEC4G|LSECtin
- Protein/peptide name:Clec4G
- Purity:>85% as determined by SDS-PAGE.
- Molecular weight:52.1 kDa
- Formulation:Lyophilized, 50 mM tris, 100 mM glycine, pH7.5
- Tested applications:Western Blot
Specifications
About this item
C-type lectin superfamily 4, member G (CLEC4G) is also known as liver and lymph node sinusoidal endothelial cell C-type lectin (LSECtin), which is a member of subgroup II of the C-type (Ca2+-dependent) lectin superfamily. CLEC4G / LSECtin binds to mannose, GlcNAc, and fucose in a Ca2+-dependent manner. In addition, CLEC4G / LSECtin has the ability to bind to surface glycoproteins of enveloped viruses. In particular, interaction of LSECtin with the surface glycoproteins of severe acute respiratory syndrome (SARS) coronavirus and Ebola virus has been described, and LSECtin-mediated infection of cells by Ebola virus has been demonstrated.