Specifications
- Antigen name:Protein Tyrosine Phosphatase, Non-receptor Type 1
- Antigen symbol:PTPN1
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Chicken
- Reactivity:Human,Rat
- Western blot:Yes
- Form:Liquid
- Antigen synonyms:PTP-HA2|CPTP1|PTN1|PTPN1|Protein-protein-tyrosine phosphatase HA2|Protein-tyrosine phosphatase 1B|Protein-tyrosine phosphatase|EC 3.1.3.48|PTP-1B|non-receptor type 1
- Concentration:1 mg/mL
- Immunogen:288-364
- Tested applications:Immunoaffinity Purified
- Size:50 µg
- Pk:50 µG
Specifications
About this item
FUNCTION: May play an important role in CKII- and p60c-src-induced signal transduction cascades (By similarity).
CATALYTIC ACTIVITY: Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
PTM: Oxidized on Cys-215; the Cys-SOH formed in response to redox signaling reacts with the beta-amido of the following residue to form a 4-amino-3-isothiazolidinone serine cross-link, triggering a conformational change that inhibits substrate binding and activity. The active site can be restored by reduction.
Tyrosine-protein phosphatase non-receptor type 1 antibody can be used for the detection of Tyrosine-protein phosphatase non-receptor type 1 by Western Blot.
Phosphate-Buffered Saline. No preservatives added.
Phosphate-Buffered Saline. No preservatives added.
Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Type:
Antigen: PTPN1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Chicken
Isotype:
Reactivity: Human, Rat