Anti-CDKN1A Rabbit Polyclonal Antibody (Alexa Fluor® 555)
Catalog # BOSSBS-5237R-A555
Supplier: Bioss
Specifications
- Antibody type:Primary
- Antigen name:Cyclin-dependent kinase inhibitor 1A
- Antigen symbol:CDKN1A
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 555
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Cross adsorption:No
- Form:liquid
- Gene ID:1026
- Antigen synonyms:p21WAF|CDKI|P21|mda6|CAP20|SDI1|p21Cip1|CIP1|Waf1|Cdkn1
- Modification:phospho-Thr145
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Immunogen:96-146/164
- Purification:Purified by Protein A
- Pk:100 µl
Specifications
About this item
May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex.
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: CDKN1A
Clonality: Polyclonal
Clone: 0
Conjugation: Alexa Fluor® 555
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: