The HI30 antibody reacts with human CD45, one of the most abundant hematopoietic markers and one that is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, CD45RO and others.
The HI30 antibody is widely used as a marker for human CD45 expression on T cells, B cells, monocytes, macrophages, and NK cells.
Type: Primary
Antigen: PTPRC (protein tyrosine phosphatase, receptor type, C)
Clonality: monoclonal
Clone: HI30
Conjugation: APC (Allophycocyanin)
Epitope:
Host: Mouse
Isotype: IgG1 Kappa
Reactivity:
- Catalog No:
- 20-0459-T025
- 20-0459-T100
- 20-0459-T500
- Antigen symbol:
- PTPRC
- PTPRC
- PTPRC
- Antigen name:
- Protein tyrosine phosphatase receptor type C
- Protein tyrosine phosphatase receptor type C
- Protein tyrosine phosphatase receptor type C
- Antigen synonyms:
- CD45R|B220|CD45|GP180|T200|L-CA|LY5|receptor type C|LCA|protein tyrosine phosphatase
- CD45R|B220|CD45|GP180|T200|L-CA|LY5|receptor type C|LCA|protein tyrosine phosphatase
- CD45R|B220|CD45|GP180|T200|L-CA|LY5|receptor type C|LCA|protein tyrosine phosphatase
- Antibody type:
- Primary
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Monoclonal
- Conjugation:
- APC (Allophycocyanin)
- APC (Allophycocyanin)
- APC (Allophycocyanin)
- Clone:
- HI30
- HI30
- HI30
- Reactivity:
- Chimpanzee, Human
- Chimpanzee, Human
- Chimpanzee, Human
- Host:
- Mouse
- Mouse
- Mouse
- Gene ID:
- 5788
- 5788
- 5788
- Isotype:
- IgG1 kappa
- IgG1 kappa
- IgG1 kappa
- Western blot:
- Yes
- Yes
- ImmunoChemistry:
- Yes
- Yes
- ImmunoPrecipitation:
- Yes
- Yes
- Flow cytometry:
- Yes
- Yes
- Yes
- Cross adsorption:
- none
- none
- Storage temperature:
- Cool
- Cool
- +2 °C to +8 °C, protected from light
- Shipping temperature:
- Ice
- Ice