Anti-FISH Rabbit Polyclonal Antibody

Catalog # BOSSBS-11645R

Supplier: Bioss

Catalog # BOSSBS-11645R

Supplier: Bioss

Specifications

Antibody type:
Primary
Antigen name:
Five SH3 domain-containing protein
Antigen symbol:
FISH
Clonality:
Polyclonal
Conjugation:
Unconjugated
Host:
Rabbit
ImmunoChemistry:
Yes
Isotype:
IgG
Reactivity:
Human,
Rat,
Mouse
Environmentally Preferable:
Form:
liquid
Antigen synonyms:
SH3 multiple domains protein 1|TKs5|Tyrosine kinase substrate with five SH3 domains.|Adapter protein TKS5|Sh3md1|SPD2A_HUMAN|SH3 and PX domain-containing protein 2A|Five SH3 domain-containing protein|Sh3pxd2a
Storage buffer:
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0,09% sodium azide. Store at -20°C for 12 months.
Concentration:
1 ug/ul
Shipping temperature:
4 °C
Purification:
Purified by Protein A.
Size:
100 μg
Pk:
100 µl

Specifications

About this item

Fish, a potential Src substrate, is a broadly expressed adaptor protein containing five SH3 domains and a phox homology (PX) domain (1). The Src family of protein tyrosine kinases act in signal transduction pathways (2-4). Src kinases vary in expression but are strongly regulated in vivo; catalytic activity is repressed by interacting with the SH3 domain (5-7). In Src-transformed fibroblasts and in normal cells treated with certain growth factors fish is tyrosine-phosphorylated (1). Treatment of cells with cytochalasin D results in rapid tyrosine phosphorylation of fish, along with activation of Src (1). Fish is likely to be involved in tyrosine kinase signaling and may have a role in cytoskeletal changes (1).

IHC-P(1:100-500), IF(IHC-P)(1:50-200)

Type: Primary
Antigen: FISH
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat