"Solid Phase Extraction"

Supplier: VARIAN

Bond Elut™ C18 OH is a non-end capped version of the octadecyl bonded phases that enables the silanols on the silica surface to be more active. This low-load C18 has well-controlled silanol activity that permits the fractionation of metabolites and enhances retention of basic compounds compared to an endcapped C18. The pore size makes it a good choice for peptide extraction.

Supplier: GILSON LCMS

This ASPEC® system for positive pressure solid phase extraction (SPE) automation maximises throughput by processing up to four samples in parallel. With its small footprint and multiple probes, it is the ideal choice for reproducible and efficient sample cleanup for clinical, forensic, doping, food, and environmental testing labs.

Supplier: VARIAN

Bond Elut™ LMS polymeric sorbent lets you elute without having to add amine modifiers, buffers, or acids. The elimination of secondary interactions means that elution of analytes can be achieved with pure organic solvents or HPLC mobile phase-compatible solvent mixtures of low ionic strength. These characteristics are crucial to allow compatibility with LC/MS or other delicate analytical techniques.

Supplier: VARIAN

CBA is a mid-polarity sorbent and weak cation exchanger (pKa 4,8). It can be used with a wider range of counter-ions than lower pKa sorbents like SCX and will demonstrate easier elution of quaternary amine functionalised analytes.

Supplier: VARIAN

Bond Elut™ PH is a non-polar bonded silica material which exhibits a different selectivity to alkyl or aliphatic functionalised phases such as C8 or cyclohexyl. The electron density present in the aromatic ring affords an enhancement in the retention of conjugated or aromatic ring-containing analytes due to desirable pi-pi interactions.

Supplier: VARIAN

Solid phase microextraction (SPME) is a technique for extracting analytes from solid, liquid or gaseous samples by adsorbing them onto the SPME fiber and then desorbing them into an inlet, either on a gas chromatograph (GC) or an HPLC system. SPME is amenable to automation using an autosampler or it can be performed manually as well.

Supplier: VARIAN

Florisil is a magnesia-loaded silica gel, extremely polar in nature and ideal for the isolation of polar compounds from non-polar matrices.

Supplier: VARIAN

Bond Elut™ PPL is a styrene-divinylvenzene (SDVB) polymer that has been modified with a proprietary non-polar surface. PPL will retain even the most polar classes of analytes, including phenols. The large particle size allows ease of flow for viscous or particulate rich water samples, while the high surface area and strong hydrophobicity ensure reproducible extractions with high recoveries upon elution. Bond Elut™ PPL is suitable for EPA Method 528 ‘Determination of Phenols in Drinking Water by SPE and Capillary GC/MS’.

Supplier: VARIAN

Native silica is generally regarded as the most polar SPE sorbent available. Bond Elut™ SI is particularly effective at separating compounds with a very similar structure. Applying the analytes in a non-polar solvent, then increasing the solvent polarity by increasing the concentration of a polar modifier, such as THF or ethyl acetate, delivers effective separations.

Supplier: Whatman products (Cytiva)

The 10 ml UNIFILTER is used with large sample or reagent volumes. Typical applications include biomolecule purification by solid phase extraction and organic synthesis in combinatorial chemistry library generation.

Supplier: WATERS

These cartridges can used with liquid and gas samples and have the unique capability of reverse flow direction, a useful feature for trace enrichment application.

Supplier: VARIAN

Bond Elut™ DEA bears some resemblance to Bond Elut™ NH₂ in its properties but with a slightly lower capacity as an anion exchange sorbent. DEA has a moderately non-polar character due to the alkyl side chains on the amino functionality. These groups still afford a medium level of polarity, higher than C₈ but less polar than C₂ or CN-E.

Supplier: Thermo Fisher Scientific

Solid Phase Micro Extraction (SPME) uses a thin-fused silica fiber coated with a sorbent which enables extraction of compounds of interest from liquid or gaseous samples through absorption or adsorption. The fiber is then moved to the injector and the compounds thermally desorbed. The SPME consumables come in two formats SPME fibers and SPME arrows.

Supplier: VARIAN

Bond Elut™ Certify II was developed specifically for the rapid and effective extraction of acidic drugs and metabolites from urine and other biological matrices. Certify II is a mixed-mode cartridge packed with non-polar C8 and strong anion exchange (SAX) sorbent. It has been optimised for acidic drugs such as 11-nor-delta-9-tetrahydrocannibinol-carboxylic acid, salicylic acid, ibuprofen, acetaminophen and other compounds that possess both non-polar and anionic characteristics.

Supplier: VARIAN

PBA is a unique sorbent consisting of a phenylboronic acid covalently linked to a silica gel surface. Covalent processes result in a higher retention to the sorbent surface than other mechanisms, resulting in superior clean-up. The boronate group has a high specificity for cis-diol containing compounds such as catechols, nucleic acids, low molecular weight proteins and carbohydrates.

Supplier: VARIAN

Bond Elut™ PRS is a strong cation exchange sorbent that is also relatively high in polarity. With no appreciable degree of hydrophobicity, in non-polar solvents, PRS is capable of polar and hydrogen bonding interactions. Due to the very low pKa of PRS, a high ionic strength eluent must be used, and so the use of PRS is recommended for weaker cationic species such as pyridinium compounds.