"Other Essentials"

Supplier: Abcam

Anti-CLEC9A antibody [EPR24271-117] is a Rabbit Monoclonal antibody that is used in CLEC9A Flow Cytometry (Intra), IHC-P. Suitable for Mouse samples. C-type lectin domain containing 9A (Clec9a) is an endocytic receptor that recognizes danger signals exposed on necrotic cells. It's essential for the cross-presentation of dead cell-associated antigens, which is crucial for initiating innate immune responses.

Supplier: Abcam

Anti-PRDM1/Blimp1 antibody [EPR25163-80] is a Rabbit Monoclonal antibody that is used in PRDM1/Blimp1 IHC-P, IP, Western Blot. Suitable for Human samples. PRDM1(Blimp1) is a transcription factor that plays a crucial role in the differentiation of plasma cells and CD8+ effector T cells. It regulates the expression of genes involved in immune responses and is essential for the terminal differentiation and function of various immune cell.

Supplier: Abcam

Anti-Anti antibody [RP23040238] is a Rabbit Recombinant Multiclonal antibody that is used in Anti ICC/IF, Western Blot. Suitable for Human, Mouse samples. Liver arginase, particularly arginase-1 (ARG1), plays a significant role in cancer by regulating the proliferation, migration, and apoptosis of cancer cells. It contributes to immunosuppression and promotes the synthesis of polyamines, which are essential for tumor growth. Targeting arginase activity is being explored as a potential therapeutic strategy to inhibit cancer progression.

Supplier: BIOMOL RESEARCH LABORATORIES

DegP acts as a chaperone at low temperatures but switches to a peptidase (heat shock protein) at higher temperatures. It degrades transiently denatured and unfolded proteins which accumulate in the periplasm following heat shock or other stress conditions.

Supplier: Trajan Scientific and Medical

Gas purifiers are designed to provide fast stabilisation times to reduce gas consumption and provide clean gas to GC and GC/MS systems.

Supplier: Abcam

Recombinant Human IKK gamma/NEMO protein is a Human Full Length protein, in the 1 to 419 aa range, expressed in Baculovirus infected Sf9, with =95% purity and suitable for SDS-PAGE, WB.

Supplier: Biotium

MTS, TS and maleimide, and other thiol-modifying reagents and reactive fluorescent dyes.

Supplier: Abcam

Anti-Brd4 antibody [EPR29186-23] is a Rabbit Monoclonal antibody that is used in Brd4 Dot Blot, IHC-P, Western Blot. Suitable for Human, Mouse, Rat samples. BRD4 (Bromodomain-containing protein 4) is a chromatin reader protein that recognises and binds acetylated histones, playing a crucial role in transcription regulation. It is part of the BET (bromodomain and extra terminal domain) family, which includes BRD2, BRD3, and BRDT. BRD4 is involved in maintaining epigenetic memory across cell divisions and is essential for the expression of certain oncogenes in various cancers.

Supplier: Abcam

Anti-DDX6 antibody [EPR27016-10] is a Rabbit Monoclonal antibody that is used in DDX6 ICC/IF, IHC-P, IP, Western Blot. Suitable for Human, Mouse, Rat samples. DDX6 is an RNA helicase involved in the regulation of mRNA metabolism, including translation suppression and mRNA degradation. It plays a crucial role in the formation of P-bodies and stress granules, which are essential for the storage and decay of mRNAs. Additionally, DDX6 is required for microRNA-induced gene silencing, impacting gene expression regulation.

Supplier: Abcam

Anti-KMT2B/MLL4 C-terminal antibody [EPR27970-7] is a Rabbit Monoclonal antibody that is used in KMT2B/MLL4 ChIP-seq, Dot Blot, Western Blot. Suitable for Human, Mouse, Rat samples. KMT2B (MLL4) is a histone methyltransferase that specifically methylates histone H3 at lysine 4 (H3K4), playing a key role in gene regulation. It is involved in chromatin remodeling and is essential for the regulation of developmental genes and stem cell differentiation. Mutations in KMT2B have been linked to various cancers and developmental disorders.

Supplier: Abnova

This Protein Phosphorylation Antibody Pair set comes with two Antibodies, one against the IKBKG protein, and the other against the specific S31 phosphorylated site of IKBKG for use in Proximity Ligation Assay

Supplier: ROBU GLASFILTER

ROBU® Filter Crucibles with intergrated VitraPOR® filter provide efficient filtration for laboratory applications. Made from durable materials, these crucibles are designed for high-performance filtration, offering reliable separation of solids and liquids. Ideal for gravimetric analysis and other precise filtration processes.

Supplier: Abcam

Anti-CD3D+CD3G+CD3 epsilon antibody [RM1128] is a Rabbit Recombinant Multiclonal antibody that is used in CD3D+CD3G+CD3 epsilon Flow Cytometry (Intra), ICC/IF, IHC-P, IP, Western Blot. Suitable for Human, Mouse, Rat samples. CD3 is a protein complex found on T cells that is essential for T-cell receptor signaling and activation. In cancer research, CD3-targeted therapies, such as bispecific antibodies, are used to engage T cells and enhance their ability to recognize and destroy tumor cells. This approach has shown promise in treating various cancers, including both hematologic and solid malignancies.

Supplier: Abcam

Anti-HIRA/HIR antibody [EPR25299-11] is a Rabbit Monoclonal antibody that is used in HIRA/HIR IHC-P, IP, Western Blot. Suitable for Human, Mouse, Rat samples. HIRA (Histone Cell Cycle Regulator) is a histone chaperone that facilitates replication-independent chromatin assembly by placing the variant histone H3.3 into nucleosomes. It plays a crucial role in the formation of senescence-associated heterochromatin foci (SAHF), which are involved in the irreversible cell cycle changes in senescent cells. Additionally, HIRA is essential for the periodic repression of histone gene transcription during the cell cycle.

Supplier: Bioss

ADCK2 (aarF domain containing kinase 2), also known as AARF, is a 626 amino acid single-pass membrane protein belonging to the protein kinase superfamily and the ADCK protein kinase family. The ADCK family consists of five paralogs in human (ADCK1-5). Encoded by a gene that maps to human chromosome 7q34, ADCK2 contains one protein kinase domain. ADCK2 participates in ATP and nucleotide binding, transferase functions and protein serine/threonine kinase activities. Expression of ADCK2 inversely correlates with cellular viability, suggesting elevated expression of ADCK2 may be essential for tumour survival. ADCK2 is necessary for cell proliferation of glioblastoma multiforme (GBM), a fatal primary brain tumor containing countless genetic and epigenetic alterations.

Supplier: Cayman Chemical

TAK-242 ≥98%