1064 Ergebnisse für: "Other Essentials"

Supplier: Bioss

Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signal transduction of TRAF6, various cytokines including interleukin-1 (IL-1), transforming growth factor-beta (TGFB), TGFB-related factors like BMP2 and BMP4, toll-like receptors (TLR), tumor necrosis factor receptor CD40 and B-cell receptor (BCR). Ceramides are also able to activate MAP3K7/TAK1. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade and the p38 MAPK signal transduction cascade through the phosphorylation and activation of several MAP kinase kinases like MAP2K1/MEK1, MAP2K3/MKK3, MAP2K6/MKK6 and MAP2K7/MKK7. These MAP2Ks in turn activate p38 MAPKs, c-jun N-terminal kinases (JNKs) and I-kappa-B kinase complex (IKK). Both p38 MAPK and JNK pathways control the transcription factors activator protein-1 (AP-1), while nuclear factor-kappa B is activated by IKK. MAP3K7 activates also IKBKB and MAPK8/JNK1 in response to TRAF6 signaling and mediates BMP2-induced apoptosis. In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK1, but not that of NF-kappa-B. Promotes TRIM5 capsid-specific restriction activity.

Supplier: Boster Bio

Rabbit IgG polyclonal antibody for Galectin-8(LGALS8) detection. Tested with WB in Human;Rat.

Supplier: Bioss

MAP2K1
Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation. RAF1 then further activates the dual-specificity protein kinases MAP2K1/MEK1 and MAP2K2/MEK2. Both MAP2K1/MEK1 and MAP2K2/MEK2 function specifically in the MAPK/ERK cascade, and catalyse the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in the extracellular signal-regulated kinases MAPK3/ERK1 and MAPK1/ERK2, leading to their activation and further transduction of the signal within the MAPK/ERK cascade. Depending on the cellular context, this pathway mediates diverse biological functions such as cell growth, adhesion, survival and differentiation, predominantly through the regulation of transcription, metabolism and cytoskeletal rearrangements. One target of the MAPK/ERK cascade is peroxisome proliferator-activated receptor gamma (PPARG), a nuclear receptor that promotes differentiation and apoptosis. MAP2K1/MEK1 has been shown to export PPARG from the nucleus. The MAPK/ERK cascade is also involved in the regulation of endosomal dynamics, including lysosome processing and endosome cycling through the perinuclear recycling compartment (PNRC), as well as in the fragmentation of the Golgi apparatus during mitosis.

Supplier: TEMPSHIELD

Waterproof Cryo-Grip® gloves offer improved grip on small objects while protecting hands and arms when working in hasardous, ultra-cold environments.

Supplier: Boster Bio

Rabbit IgG polyclonal antibody for Transcription factor SOX-1(SOX1) detection. Tested with WB in Human;Mouse;Rat.

Supplier: THERMO SAVANT

The Thermo Scientific™ Savant™ SpeedVac™ SPD120 vacuum concentrator can be used with a wide variety of solvents and offers resistance to methanol, acetonitrile with 0.1% TFA, and other aggressive solvents used in DNA and biological samples. With a medium-capacity, modular[1] design, the SPD120 vacuum concentrator can also be used for applications where freeze-drying or lyophilisation is needed.

Supplier: THERMO SAVANT

The Thermo Scientific™ Savant™ SpeedVac™ SPD120 vacuum concentrator can be used with a wide variety of solvents and offers resistance to methanol, acetonitrile w/ 0.1% TFA, and other aggressive solvents used in DNA and biological samples. With a medium-capacity, modular[1]design, the SPD120 vacuum concentrator can also be used for applications where freeze-drying or lyophilization is needed.

Supplier: Boster Bio

Rabbit IgG polyclonal antibody for Kininogen-1(KNG1) detection. Tested with WB, IHC-P in Mouse.

Supplier: Thermo Fisher Scientific

The Pierce Glycoprotein Staining Kit is a convenient, fast, and sensitive colorimetric kit for staining glycosylated proteins in polyacrylamide gels or nitrocellulose membranes using the periodic acid-Schiff (PAS) method.

Supplier: THERMO SAVANT

The Thermo Scientific™ Savant™ SpeedVac™ SPD130DLX vacuum concentrator is a medium-capacity, vacuum concentrator with a modular design. It is compatible with a wide variety of solvents and offers resistance to TFA, DMSO, and other aggressive solvents used in combinatorial chemistry applications.

Supplier: Boster Bio

Rabbit IgG polyclonal antibody for Prolactin(PRL) detection. Tested with WB, ELISA in Human.

Supplier: VWR Collection

Designed for for PFAS analysis, these kits contain 0,7 ml polypropylene snap ring vials with silicone white/polypropylene transparent septum, available with or without slit.

Supplier: Boster Bio

Rabbit IgG polyclonal antibody for Mothers against decapentaplegic homolog 3(SMAD3) detection. Tested with WB in Human.

Supplier: MP Biomedicals

RPMI 1640 medium was originally developed to culture human leukaemic cells in suspension and as a monolayer. Roswell Park Memorial Institute (RPMI) 1640 Medium has since been found suitable for a variety of mammalian cells, including HeLa, Jurkat, MCF-7, PC12, PBMC, astrocytes, and carcinomas. RPMI has successfully been used for the cultivation of normal human and neoplastic leukocytes. It is now a popular general purpose medium when properly supplemented.

Supplier: MP Biomedicals

Acetyl-CoA is produced via beta-oxidation of fatty acids, via the metabolism of carbohydrates - glucose 6-phosphate to pyruvate to acetyl-CoA and via the catabolism of amino acids. Acetyl-CoA has a number of metabolic opportunities. It is metabolised in the tricarboxylic acid cycle to produce carbon dioxide, water and energy.

Supplier: Corning

The efficient removal of unincorporated dNTPs, salts and enzymes after any PCR is detrimental to the success or failure of downstream applications, such as genotyping, Sanger, and Next Generation Sequencing. The AxyPrep™ Mag PCR Clean Up Kit utilises a paramagnetic bead technology for rapid high throughput purification of PCR products. Additionally, the AxyPrep™ Mag PCR Clean Up Kit employs an optimised buffer to selectively bind PCR amplicons 60 bp and larger to paramagnetic beads, providing end users flexibility and high recovery options. The protocol comprises binding, washing and eluting steps, where primers, nucleotides, salts and enzymes in the reaction mixture are efficiently removed leaving a purified PCR product that is essentially free of contaminants. No centrifugation or filtration steps are required, allowing the process to be adapted to multiple commercially available automation platforms.

Supplier: MP Biomedicals

Cholesterol is the principal sterol of the higher animals, found in all body tissues. It is the main constituent of gallstones and all biological membranes. Approximately 25% of total brain lipid is cholesterol.

Supplier: Boster Bio

Rabbit IgG polyclonal antibody for Apolipoprotein E(APOE) detection. Tested with WB, IHC-P in Human.

Supplier: Thermo Fisher Scientific

The Pierce™ Crosslink Magnetic IP/Co-IP Kit uses crosslinking chemistry to covalently immobilise IP antibodies onto premium-quality protein A/G magnetic beads for effective immunoprecipitation and co-immunoprecipitation.

Supplier: Boster Bio

Rabbit IgG polyclonal antibody for Potassium voltage-gated channel subfamily A member 3(KCNA3) detection. Tested with WB in Human;Mouse;Rat.

Supplier: Cytiva

illustra™ AutoSeq™ G-50 columns are specifically designed to remove fluorescent dye-terminators from sequencing reactions prior to analysis on automated sequencers. Effective purification is essential for high quality sequencing results since residual dye-terminators can obscure data. illustra™ AutoSeq™ G-50 consists of MicroSpin™ columns containing Sephadex™ G-50, pre-equilibrated in double-distilled water. This is important because even the small amount of salt in traditional buffers (such as TE buffer) can cause electrophoretic artifacts on salt-sensitive automated sequencers.

Supplier: MP Biomedicals

Dissolves readily at 5 mg/ml in 0,01 M Sodium Phosphate pH 7,5 to give a clear colourless solution.

Supplier: Boster Bio

Rabbit IgG polyclonal antibody for 78 kDa glucose-regulated protein(HSPA5) detection. Tested with WB, IHC-P in Human;Mouse;Rat.

Supplier: ROBU GLASFILTER

ROBU® gas washing bottle with large VitraPOR® filter disc and NS 29/32 or NS 45/40 standard joint ensures efficient gas absorption in laboratory applications.

Supplier: VWR Collection

PFAS stands for per- and polyfluoroalkyl substances, and are colloquially known as ‘forever chemicals’. Available with or without a pre-slit septum.

Supplier: VWR Collection

Vials, 1,5 ml PP, with 9 mm short thread cap, silicone/polypropylene.

Supplier: VWR Collection

PFAS stands for per- and polyfluoroalkyl substances, and are colloquially known as ‘forever chemicals’. Available with or without a pre-slit septum.

Supplier: Molecular Devices

This UV-visible absorbance microplate reader provides ultrafast, full spectral range detection for cuvettes, 96-well, and 384-well microplates, with the only temperature-independent method for pathlength correction.

Supplier: Boster Bio

Rabbit IgG polyclonal antibody for Thioredoxin-dependent peroxide reductase, mitochondrial(PRDX3) detection. Tested with WB, IHC-P in Human;Mouse;Rat.

Supplier: Boster Bio

Rabbit IgG polyclonal antibody for Transcription factor SOX-2(SOX2) detection. Tested with WB, IHC-P in Human;Mouse;Rat.