12525 Ergebnisse für: "Enzo Life Sciences"
Cyclo [Arg-Gly-Asp-D-Phe-Val]
Supplier: ENZO LIFE SCIENCES
Integrin αvβ3 antagonist. Inhibits cell adhesion events mediated by αvβ3. Inhibits angiogenesis. Induces rapid regression of histologically distinct human tumors. Induces apoptosis of angiogenic blood vessels.
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Fluor-de-Lys® SIRT2 fluorometric drug discovery assay kit
Supplier: ENZO LIFE SCIENCES
A Fluor-de-Lys® fluorescent assay system. The SIRT2 Fluorescent Activity Assay/Drug Discovery Kit is a complete assay system designed to measure the lysyl deacetylase activity of the recombinant human SIRT2 included in the kit. The kit is ideal for chemical library screening for candidate inhibitors or activators or kinetic assay of the enzyme under varying conditions.
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Fluor-de-Lys® SIRT1 fluorometric drug discovery assay kit
Supplier: ENZO LIFE SCIENCES
A Fluor-de-Lys® fluorescent assay system. The SIRT1 Fluorescent Activity Assay/Drug Discovery Kit is a complete assay system designed to measure the lysyl deacetylase activity of the recombinant human SIRT1 included in the kit.
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Why Choose Corning Fetal Bovine Serum?
Our vertically integrated FBS serum supply chain, from collection to scientist, allows us to provide a consistent supply of FBS.
PTP1B drug discovery kit
Supplier: ENZO LIFE SCIENCES
The PTP1B Tyrosine Phosphatase Drug Discovery Kit is a colorimetric, non-radioactive assay designed to measure the phosphatase activity of purified PTP1B. This 96-well assay is useful for screening inhibitors and modulators of PTP1B activity.
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Niguldipine hydrochloride ≥98%
Supplier: ENZO LIFE SCIENCES
Ca²⁺ channel blocker
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SKF-96365 hydrochloride ≥98% (durch HPLC)
Supplier: ENZO LIFE SCIENCES
A novel, selective inhibitor of receptor-mediated calcium entry. It inhibits receptor-mediated calcium entry in stimulated platelets (IC50=8-12µM) neutrophils and endothelial cells at concentrations which do not affect internal Ca²⁺ release. Note, in some cells SK&F 96365 can activate a novel Ca²⁺ entry pathway. Blocks TRPC3 and TRPC6 activation. Inhibits the histamine-induced formation of nitric oxide in human endothelial cells.
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4-Diphenylacetoxy-N-methylpiperidine methiodide ≥98% (durch HPLC)
Supplier: ENZO LIFE SCIENCES
Acetylcholine receptor ligand.
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Ac-Ala-Pro-Nle-Asp-H
Supplier: ENZO LIFE SCIENCES
Highly specific aldehyde based inhibitor of the caspase-like peptidic activity of the 20S proteasome.
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Anti-CK18 Mouse Monoclonal Antibody
Supplier: ENZO LIFE SCIENCES
Host: Mouse, Isotype: IgG1
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(±)1,2-Didecanoylglycerol (10:0) ≥98% (durch TLC), weißer Feststoff
Supplier: ENZO LIFE SCIENCES
PKC activator.
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Oxatomide ≥99% (durch HPLC)
Supplier: ENZO LIFE SCIENCES
Suppresses PAF-induced bronchoconstriction in the guinea pig (ED50=0.9 mg/kg orally).
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Dibutyryl-cAMP sodium salt ≥98% (durch HPLC)
Supplier: ENZO LIFE SCIENCES
PKA activator.
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Shikonin ≥98% (durch HPLC)
Supplier: ENZO LIFE SCIENCES
Shikonin inhibits TNF-α- and B6 melanoma-induced angiogenesis in mice. It blocks expression of integrin αvβ3 and inhibits endothelial cell proliferation and migration in vitro.
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Rp-8-Br-cGMPS ≥98% (durch HPLC)
Supplier: ENZO LIFE SCIENCES
Cell-permeable, phosphodiesterase-resistant cGMP antagonist. Reversed NO stimulation of random migration in rabbit neutrophils. Used at 30µM to cometively inhibit 8-Br-cGMP relaxation of rabbit aortas. The product is not sterile. Resistant to nucleotide-dependent phosphodiesterases; no metabolic side effects. Significantly more lipophilic and membrane permeant as compared to cyclic GMP or Rp-cGMPS.
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Cytochalasin E ≥98% (durch HPLC, TLC)
Supplier: ENZO LIFE SCIENCES
Inhibits angiogenesis
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1-O-Hexadecyl-2-O-acetyl-sn-glycerol ≥95% (durch TLC)
Supplier: ENZO LIFE SCIENCES
Inhibits protein kinase C activation by diacylglycerols. Stimulates HL-60 cell differentiation. Biosynthetic precursor of PAF via remodeling and retroconversion/de novo routes. Induces delayed aggregation of rabbit platelets. Mitogenic for smooth muscle cells.
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(R)-(-)-Deprenyl hydrochloride ≥98% (durch HPLC)
Supplier: ENZO LIFE SCIENCES
Deprenyl inhibits apoptosis and displays neuroprotective effects in a variety of in vitro and in vivo systems. In vivo it rescues nigral dopaminergic neurons after systemic MPTP treatment. In vitro it rescues PC12 cells from apoptotic cell death induced by trophic withdrawal. The putative target responsible for the anti-apoptotic effects is glyceraldehyde-3-phosphate dehydrogenase. Deprenyl also inhibits monoamine oxidase-B, which is not involved in its anti-apoptotic mechanism. Parkinson’s disease therapeutic.
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1-Aminobenzotriazol ≥99%
Supplier: ENZO LIFE SCIENCES
Cytochrome P450 inhibitor
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L-Buthionine sulphoximine ≥97% (durch TLC)
Supplier: ENZO LIFE SCIENCES
L-Buthionine-sulfoximine (BSO) induces oxidative stress in cells by irreversibly inhibiting γ-glutamylcysteine synthetase, an essential enzyme for the synthesis of glutathione.
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N,N'-Di(2-hydroxybenzyl)ethylenediamine-N,N'-diacetic acid monohydrochloride hydrate (HBED) ≥95% (durch NMR)
Supplier: ENZO LIFE SCIENCES
Potent iron chelator
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Bordetella pertussis toxin
Supplier: ENZO LIFE SCIENCES
Bordetella pertussis toxin (Islet-activating protein, PTX) from Bordetella pertussis, strain NCTC 10739. is a high purity toxin applicable to ELISA, antibody capture, cytotoxicity studies, LINE assay.