Supplier: ENZO LIFE SCIENCES

Supersensitive spin label

Supplier: ENZO LIFE SCIENCES

Cyclic hydroxylamine spin probe for in vivo, intraperitoneal and intravenous injections.

Supplier: ENZO LIFE SCIENCES

Cyclic hydroxylamine spin probe for in vivo, intraperitoneal and intravenous injections.

Supplier: ENZO LIFE SCIENCES

The Screen-Well® Wnt pathway library v 2.0 is a focused collection of 71 compounds with defined and diverse Wnt pathway activity, including activators and inhibitors of Wnts, Dishevelled, GSK-3β and other Wnt pathway kinases, TCF/β-catenin, DKK, LRP, Axin, Porcupine, and more. Compounds are dissolved in DMSO at 10 mM or 1 mM and aliquoted into deep-well plates at 100 or 500 µl per well. A variety of structurally and mechanistically different compound classes are included. A useful tool for studying the roles of pro- and anti-Wnt pathway molecules in cells as well as for use in in vitro applications.

Supplier: ENZO LIFE SCIENCES

The lymphocyte activation gene-3 (LAG-3, CD223), a member of the immunoglobulin superfamily (IgSF) related to CD4, binds to the major histocompatibility complex (MHC) class II molecules but with higher affinity than CD4. Several alternative mRNA splice-variants of human LAG-3 have been described, two of them encoding potential secreted forms: LAG-3V1 (i.e. the D1-D2 domains of the protein, 36 kDa) and LAG-3V3 (D1-D3, 52 kDa). The longer form was detected by ELISA in the serum of healthy individuals as well as of tuberculosis patients with a favorable outcome. LAG-3 expression by T cell clones correlated with IFN-γ production, and hence soluble LAG-3 has been suggested as a serological marker of Th1 responses.

Supplier: ENZO LIFE SCIENCES

The lymphocyte activation gene-3 (LAG-3, CD223), a member of the immunoglobulin superfamily (IgSF) related to CD4, binds to the major histocompatibility complex (MHC) class II molecules but with higher affinity than CD4. Several alternative mRNA splice-variants of human LAG-3 have been described, two of them encoding potential secreted forms: LAG-3V1 (i.e. the D1-D2 domains of the protein, 36 kDa) and LAG-3V3 (D1-D3, 52 kDa). The longer form was detected by ELISA in the serum of healthy individuals as well as of tuberculosis patients with a favorable outcome. LAG-3 expression by T cell clones correlated with IFN-γ production, and hence soluble LAG-3 has been suggested as a serological marker of Th1 responses.

Supplier: ENZO LIFE SCIENCES

Quantitative protein standards for Western blotting internal controls or ELISA standards.

Supplier: ENZO LIFE SCIENCES

Human Recombinant HGF (from Insect cells)

Supplier: Enzo Life Sciences

Host: Rabbit

Supplier: Enzo Life Sciences

Fodrin, also referred to as non-erythroid (αII-; brain) spectrin, is a tetrameric (αγ)2 actin-binding, fibrous protein, widely distributed in vertebrates, which forms part of the sub-membranous cytoskeleton within many cell types including neurons, and is particularly abundant with axons. The α-subunits of fodrins and spectrin are highly conserved phylogenetically, with the exception of human α-fodrin, which shares only 55-59% homology with erythroid-specific α-spectrins. The β-subunits of spectrin (and γ-subunits of fodrins) are species specific. The interleukin-1 converting enzyme (ICE) family of proteases has been implicated as important effectors of the apoptotic pathway, perhaps acting hierarchically in a protease cascade. Neuronal fodrin is known to be cleaved by calpain following ischaemic insult and it has been proposed that calpain and an unidentified protease play a role in the onset of neuronal death following transient forebrain ischaemia. Recently, an ICE-like protease has been implicated in the early cleavage of fodrin, producing a 150kDa fragment, proximal to CPP32 in Fas-induced and C2-ceramide mediated apoptosis. A cleavage product of α-fodrin has been proposed as a candidate autoantigen in primary Sjögren’s syndrome and α-fodrin has been shown to be the source of a so-called ‘inhibitory protein factor’ family, members of which have been shown to inhibit both GABA and ATP-dependent glutamate uptake into purified synaptic vesicles.

Supplier: Enzo Life Sciences

Host: Rabbit

Supplier: Enzo Life Sciences

Host: Rabbit

Supplier: Enzo Life Sciences

Host: Rabbit

Supplier: Enzo Life Sciences

Produced in E. coli.

Supplier: Enzo Life Sciences

Sequence derived from human/mouse dishevelled-2 [Cys+600-614]. Used to generate the rabbit polyclonal antiserum to dishevelled-2 (BML-DA4270).

Supplier: Enzo Life Sciences

Immunization and blocking peptide for Glutamic Acid Decarboxylase (GAD) antibodies (BML-GC3008 and BML-GC3108).

Supplier: Enzo Life Sciences

Prevents neurotoxicity of glutamate on neuronal cells.

Supplier: Enzo Life Sciences

Semisynthetic (from GM1).

Supplier: Enzo Life Sciences

Produced in E. coli.

Supplier: Enzo Life Sciences

PKCβ inhibitor

Supplier: Enzo Life Sciences

PTP inhibitor, PTEN Inhibitor

Supplier: Enzo Life Sciences

Inhibitor für Caspase und Granzyme

Supplier: Enzo Life Sciences

5-HT2c inhibitor

Supplier: Enzo Life Sciences

RNA polymerase II inhibitor

Supplier: Enzo Life Sciences

Produced in E. coli.

Supplier: Enzo Life Sciences

Inhibits aminopeptidases like aminopeptidase B, leucine aminopeptidase, tripeptide aminopeptidase, aminopeptidases on the surface of mammalian cells. Does not inhibit carboxypeptidases. May be used in in vitro translation system to inhibit the aminopeptidases found in reticulocate or wheat germ lysates. Activates macrophages and T lymphocytes. Immunomodulator. Has antitumor properties and enhances not only blastogenesis and lymphocytes in vitro, but also establishes a delayed-type hypersensitivity in vivo.

Supplier: Enzo Life Sciences

L(+)-Arginin

Supplier: Enzo Life Sciences

Inhibitor of caspase-1 and -4

Supplier: Enzo Life Sciences

ß-Nicotinamid-Adenin-Dinucleotid-Phosphat Tetranatriumsalz, reduzierte Form (NADPH-Na4)

Supplier: Enzo Life Sciences

Bcl-2 ligand