"Alsto"

Supplier: Apollo Scientific

An extremely potent & selective a-D-galactosidase inhibitor. Also a selective inhibitor of GlcCer synthesis.

Supplier: Bioss

The bifunctional purine biosynthesis protein ATIC (also designated PURH) contains AICAR transformylase and IMP cyclohydrolase activities. AICAR (5-aminoimidazole-4-carboxamide ribonucleotide) transformylase catalyzes the second to last step in purine biosynthesis, playing an important role in the production of nucleotides and IMP. Defects in the ATIC transformylase gene can cause AICA-rebsuria, also designated AICA-ribosiduria, an inborn error in purine biosynthesis that is neurologically cataclysmic. Individuals with AICA-rebosuria accumulate AICA-riboside, also designated ZMP, and its derivatives in erythrocytes and fibroblasts. Patients also excrete very large amounts of AICA-riboside in the urine. Mental retardation, epilepsy, dysmorphic features and congenital blindness are all symptoms of this disease.

Supplier: Bioss

Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP).

Supplier: SIGMA ALDRICH MICROSCOPY

The combination of azure A and silver staining is used for the quantification of glycosaminoglycans in agarose gels. It is also used for the staining of chromosomes in the nucleus. Azure A is a main component of the azure B/polychromed methylene blue-eosin stains family, also referred to as the Romanowsky stain. Azure A is a basic cationic dye.

Supplier: Apollo Scientific

Vismodegib is an inhibitor of hedgehog pathway with IC50 of 3 nM and also inhibits P-gp IC50 30 M.

Supplier: Bioss

MEF2C is a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. This protein controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. It may also be involved in neurogenesis and in the development of cortical architecture.

Supplier: SIGMA ALDRICH MICROSCOPY

Metanil yellow has been used for staining of leukocyte granules. It is also used as a counterstain in microscopic sections.

Supplier: Merck

Chiral derivatizing agent for alcohols; some methyl substituted primary alcohols which are difficult to separate otherwise, can also be separated.

Supplier: Bioss

Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP).

Supplier: Bioss

Plectin interlinks intermediate filaments with microtubules and microfilaments and anchors intermediate filaments to desmosomes or hemidesmosomes. Could also bind muscle proteins such as actin to membrane complexes in muscle. May be involved not only in the crosslinking and stabilization of cytoskeletal intermediate filaments network, but also in the regulation of their dynamics.

Supplier: Bioss

Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP).

Supplier: Bioss

Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP).

Supplier: Enzo Life Sciences

Phosphodiesterase PDE II inhibitor, IC50=0.8 µM. Also inhibits adenosine deaminase, Ki=4 nM.

Supplier: Abcam

Prototypic H₂ antagonist. Also an I₁ receptor agonist. Displays antitumor and immunomodulatory activity.

Supplier: Cytiva (Formerly Pall Lab)

Filtration capsules for high airflow rate venting applications. Also useful for aggressive solvent filtration.

Supplier: Bioss

The bifunctional purine biosynthesis protein ATIC (also designated PURH) contains AICAR transformylase and IMP cyclohydrolase activities. AICAR (5-aminoimidazole-4-carboxamide ribonucleotide) transformylase catalyzes the second to last step in purine biosynthesis, playing an important role in the production of nucleotides and IMP. Defects in the ATIC transformylase gene can cause AICA-rebsuria, also designated AICA-ribosiduria, an inborn error in purine biosynthesis that is neurologically cataclysmic. Individuals with AICA-rebosuria accumulate AICA-riboside, also designated ZMP, and its derivatives in erythrocytes and fibroblasts. Patients also excrete very large amounts of AICA-riboside in the urine. Mental retardation, epilepsy, dysmorphic features and congenital blindness are all symptoms of this disease.