PF-9366 ≥98%

An allosteric inhibitor of human methionine adenosyltransferase 2A (Mat2A), the extrahepatic isoform (IC₅₀ = 420 nM). PF-9366 inhibits cellular S-Adenosyl-L-methionine (SAM) production with an IC₅₀ of 1,2 μM in H520 lung carcinoma cells.

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