Horse Recombinant RE VEGF-165 (from E. coli)

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About this item

Vascular endothelial growth factor-A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. VEGF-A is a mediator of vascular growth, vascular permeability, and plays a role in stimulating vasodilation via nitric oxide-dependent pathways. VEGF-A has several alternatively spliced isoforms, with VEGF-165 being the most abundant. The VEGF-165 isoform is a secreted protein that acts on receptors VEGFR-1 and VEGFR-2 to modulate endothelial cell proliferation and angiogenesis.

High quality
Low endotoxin
Affordable

VEGF-A has several alternatively spliced isoforms, with VEGF-165 being the most abundant. The VEGF-165 isoform is a secreted protein that acts on receptors VEGFR-1 and VEGFR-2 to modulate endothelial cell proliferation and angiogenesis.

Caution: For research use only.

Specifications

Konjugation:
Unconjugated
Protein-Funktion:
Cytokine
Protein/Peptid-Typ:
Rekombinant
Ursprung:
E. coli
Spezies:
Horse
Lagerbedingungen:
−20 °C
Endotoxingehalt:
Endotoxin LAL (EU/µg) ≤0.1
Biologische Aktivität:
Bioactivity assay: HUVEC Proliferation, ED50 ≤10 ng/ml, bioactivity ≥1,0×10⁵ units/mg
Gen-ID:
Q9GKR0
Reconstitution instructions:
Sterile water at 0,1 mg/ml
Frei von Endotoxinen:
N
Frei von Trägern:
Y
Frei von Proteasen:
N
Tierfrei:
N
Proteinsynonym:
glioma-derived endothelial cell mitogen|VEGF-A|VPF
Purity:
≥95%
Molecular weight:
19,3/38,6 kDa
Sequence:
MAPMAEGEHK THEVVKFMDV YQRSYCRPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCGGC
CNDEGLECVP TAEFNITMQI MRIKPHQSQH IGEMSFLQHS KCECRPKKDK ARQENPCGPC
SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR
Endotoxinspiegel:
Low
Zusammensetzung:
10 mM sodium phosphate, pH 7,5
Frei von Nukleasen:
N
Sorte:
RUO
Transporttemperatur:
RT
Validierte Anwendungen:
Bioassay