Human/Mouse Recombinant/M NT-3 (from E. coli)

Neurotrophin-3 (NT-3) is an important member of the nerve growth factor (NGF) family of proteins. NT-3 promotes the growth, survival, and differentiation of neurons and synapses in the peripheral and central nervous systems. The receptor tyrosine kinase TrkC exclusively binds in high-affinity to NT-3. NT-3 also signals through the receptor tyrosine kinase TrkB, and through the low affinity nerve growth factor receptor (LNGFR).

High quality
Low endotoxin
Affordable

: For research use only.

Konjugation:
Unconjugated
Protein-Funktion:
Cytokine
Protein/Peptid-Typ:
Rekombinant
Ursprung:
E. coli
Spezies:
Human
Mouse
Lagerbedingungen:
At or below −20 °C
Endotoxingehalt:
Endotoxin LAL (EU/µg) ≤0.1
Biologische Aktivität:
Bioactivity assay: Proliferation of a neuroblastoma cell line stably expressing TrkB (BR6), ED50 ≤20 ng/ml, bioactivity ≥5,0×10⁴ units/mg
Gen-ID:
P20783/P20181
Reconstitution instructions:
Sterile water at 0,1 mg/ml
Frei von Endotoxinen:
N
Frei von Trägern:
Y
Frei von Proteasen:
N
Tierfrei:
N
Proteinsynonym:
nerve growth factor 2 (NGF-2)|HGNF|neurotrophic factor|NT3|Neurotrophin 3
Purity:
≥95%
Molecular weight:
13,8/27,5 kDa
Sequence:
MYAEHKSHRG EYSVCDSESL WVTDKSSAID IRGHQVTVLG EIKTGNSPVK QYFYETRCKE ARPVKNGCRG IDDKHWNSQC KTSQTYVRAL TSENNKLVGW RWIRIDTSCV CALSRKIGRT
Endotoxinspiegel:
Low
Zusammensetzung:
0,1% Trifluoroacetic Acid (TFA)
Frei von Nukleasen:
N
Sorte:
RUO
Transporttemperatur:
RT
Validierte Anwendungen:
Bioassay