Specifications
- Packung:Vial
- VE:1 KIT
- Konjugation:Unconjugated
- Protein-Funktion:Cytokine
- Protein/Peptid-Typ:Rekombinant
- Ursprung:E. coli
- Spezies:Human
- Seq:0075
- Lagerbedingungen:At or below −20 °C
- Biologische Aktivität:Bioactivity: No biological activity data is available at this time
- Frei von Endotoxinen:N
- Frei von Trägern:Y
- Frei von Proteasen:N
- Tierfrei:N
- Endotoxinspiegel:Low
- Frei von Nukleasen:N
- Sorte:RUO
- Transporttemperatur:RT
Specifications
About this item
Cytokines for polarizing human T cells into Th9 cells. Th9 cells are a unique subset of T helper cells that produce IL-9. An important function of IL-9 producing T cells is fighting inflammation and helminth infections. Th9 cells can be generated from naive CD4+ T cells in culture by culturing them in the presence of IL-4 and TGF-β 1. It also appears that IFNγ and IL-27 can inhibit the generation of Th9 cells.
- High quality
- Low endotoxin
- Affordable
Th17 cells are characterized by their ability to produce IL-17, IL-22 and IL-21. Th17 cells can be cultured from naive CD4+ T cells by culturing them in the presence of anti-CD3 and anti-CD28 stimulation with recombinant IL-6 and recombinant TGF-β 1. In some cases neutralizing antibodies against IL-12, IL-4 and IFNγ are used along with recombinat cytokines IL-1 β, IL-21 and/or IL-23.