Human/Mouse/Rat Recombinant BMP-2 (from E. coli)

Über diesen Artikel

Bone morphogenetic protein 2 (BMP-2) is a member of the bone morphogenetic protein (BMP) family and functions as a potent inducer of bone and cartilage development. BMP proteins are synthesized as large precursor molecules which are cleaved by proteolytic enzymes. Active BMP-2 consists of forming a homodimer or a heterodimer with a related BMP, such as BMP-7. BMP-2 signals through type I and type II receptor tyrosine kinases in conjuction with SMAD proteins to directly promote osteoblast differentiation. BMP-2 is also important during cardiac development and supports epicardial cell migration.

High quality
Low endotoxin
Affordable

Caution: This product is for research use only and is not for use in humans.

Spezifikationen

Konjugation:
Unconjugated
Protein-Funktion:
Cytokine
Protein/Peptid-Typ:
Rekombinant
Ursprung:
E. coli
Spezies:
Human
Rat
Mouse
Lagerbedingungen:
At or below –20 °C
Endotoxingehalt:
Endotoxin LAL (EU/µg) ≤0,1
Biologische Aktivität:
Bioactivity Assay: Alkaline phosphatase activity induced in ATDC-5 cells, ED₅₀ ≤250 ng/ml, Bioactivity ≥4,0×10³ units/mg
Gen-ID:
P12643 / P21274 / P49001
Reconstitution instructions:
Sterile water at 0,1 mg/ml
Frei von Endotoxinen:
N
Frei von Trägern:
Y
Frei von Proteasen:
N
Tierfrei:
Y
Proteinsynonym:
BMP-2A
Protein/Peptid-Name:
H/M/R BMP-2 (AF)
Purity:
≥95%
Molecular weight:
13,0/26,1 kDa
Sequence:
MQAKHKQRKR LKSSCKRHPL YVDFSDVGWN DWIVAPPGYH AFYCHGECPF PLADHLNSTN HAIVQTLVNS VNSKIPKACC VPTELSAISM LYLDENEKVV LKNYQDMVVE GCGCR
Endotoxinspiegel:
Low
Zusammensetzung:
0,1% Trifluoroacetic acid (TFA)
Frei von Nukleasen:
N
Sorte:
RUO
Transporttemperatur:
RT
Validierte Anwendungen:
Bioassay