Horse Recombinant PDGF-BB (from E. coli)

New Product

Horse Recombinant PDGF-BB (from E. coli)

New Product

Über diesen Artikel

Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by IL-1, IL-6, TNF-α, TGF-β, and EGF signaling. PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells. PDGF is also stored in the alpha-granules of platelets and is released upon adherence to traumatised tissues. PDGF is a dimeric glycoprotein formed by two A chains (AA), two B chains (BB), or as a heterodimer with an A and a B chain (AB). The PDGF dimer binds the cell surface receptor tyrosine kinases PDGFR-α and PDGFR-β.

High quality
Low endotoxin
Affordable

Caution: For research use only.

Spezifikationen

Konjugation:
Unconjugated
Protein-Funktion:
Cytokine
Protein/Peptid-Typ:
Rekombinant
Ursprung:
E. coli
Spezies:
Horse
Lagerbedingungen:
–20 °C
Endotoxingehalt:
Endotoxin LAL (EU/µg) ≤0,1
Biologische Aktivität:
Bioactivity Assay: NR6R 3T3 proliferation, ED₅₀ ≤30 ng/ml, Bioactivity ≥3,3×10⁴ units/mg
Gen-ID:
XP_005606703
Reconstitution instructions:
Sterile water at 0,1 mg/ml
Frei von Endotoxinen:
N
Frei von Trägern:
Y
Frei von Proteasen:
N
Tierfrei:
N
Proteinsynonym:
ODGF|GDGF
Protein/Peptid-Name:
PDGF-BB
Purity:
≥95%
Molecular weight:
24,8 kDa
Sequence:
MSLGSLAVAE PAMIAECKTR TEVFEISRRL IDRTNANFLV WPPCVEVQRC SGCCNNRHVQ CRPTQVQLRP VQVRKIEIVR KKPTFKKATV TLEDHLACKC ETVGAARPVT
Endotoxinspiegel:
Low
Zusammensetzung:
10 mM Sodium phosphate, pH 7,5
Frei von Nukleasen:
N
Sorte:
RUO
Transporttemperatur:
RT
Validierte Anwendungen:
Bioassay