Specifications
- Antikörper-Typ:Primär
- Antigen-Name:ferritin, light polypeptide
- Antigen-Symbol:FTL
- Klonalität:Monoklonal
- Klon:FTL/1386
- Konjugation:Unconjugated
- Durchflusszytometrie:Yes
- Wirt:Mouse
- ImmunoChemie:Yes
- ImmunFluoreszenz:Yes
- Isotyp:IgG2b
- Reaktivität:Human
- Western blot:Yes
- Format:Purified Antibody
- Form:Liquid
- Gen-ID:P02792
- Antigen-Synonyme:FTL
- Lagerungspuffer:PBS with 0,1 mg/ml BSA and 0,05% sodium azide
- Lagertemperatur:Aliquot and Store at 2…8 °C. Avoid freez-thaw cycles.
- Konzentration:0,2 mg/ml
- Transporttemperatur:4 °C
- Immunogen:Amino acids 38-165 of human FTL were used as the immunogen for this Ferritin Light Chain antibody.
- Reinigung:Protein G affinity chromatography
- Größe:100 µg
- VE:100 µG
Specifications
About this item
Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.
Western blot: 0,1-0,2 µg/ml Flow Cytometry: 0,1-0,2µg/10^6 cells IF: 0,1-0,2 µg/ml IHC (FFPE): 0,1-0,2 µg/ml for 30 min at RT The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the Ferritin Light Chain antibody to be titered up or down for optimal performance.
Type: Primary
Antigen: FTL
Clonality: Monoclonal
Clone: FTL/1386
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG2b
Reactivity: Human