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Human Recombinant DFF45 (from E. coli)
Artikelnr. PRSI92-051
Lieferant:  ProSci Inc.
New Product
CAS-Nummer:  
Human Recombinant DFF45 (from E. coli)
Artikelnr. PRSI92-051
Lieferant:  ProSci Inc.
New Product
CAS-Nummer:  

Spezifikationen

  • VE:
    0,05 mg
  • Protein/Peptid-Typ:
    Rekombinant
  • Ursprung:
    E. coli
  • Spezies:
    Human
  • Tag sequence:
    N-6 His tag
  • Lagerbedingungen:
    Store at −20 °C, stable for 6 months after receipt. Please minimise freeze-thaw cycles.
  • Endotoxingehalt:
    <0,1 ng/µg (1 IEU/µg) as determined by LAL test
  • Proteinsynonym:
    H13|DFF-45|Inhibitor of CAD|DFFA|ICAD|DNA Fragmentation Factor 45 kDa Subunit|DFF1|DNA Fragmentation Factor Subunit Alpha|DFF45
  • Protein/Peptid-Name:
    DFF45
  • Purity:
    >95% as determined by reducing SDS-PAGE
  • Molecular weight:
    38,7 kDa
  • Sequence:
    Met1-Thr331
  • Zusammensetzung:
    Supplied as a 0,2 µm filtered solution of 20 mM PB, 150 mM NaCl, pH 7,4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the Lyophilised protein in ddH₂O. Please aliquot the reconstituted solution to minimise freeze-thaw cycles.
  • Validierte Anwendungen:
    Used for biological assays

Spezifikationen

Über diesen Artikel

DNA Fragmentation Factor Subunit Alpha (DFFA). DFFA exists as a heterodimer (DFF) with DFFB. DFF is activated once DFFA is cleaved by Caspase-3. The cleaved fragments of DFFA detach from DFFB (the active component of DFF), which in turn triggers DNA fragmentation as well as chromatin condensation during apoptosis. A reduced level of DFFA detected in ovarian endometriosis may be a part of an apoptosis-resistant mechanism enhancing the disease progression.

  • Fusion-Tag: N-6 His tag

This recombinant protein can be used for biological assays.

Caution: For research use only.