Spezifikationen
- VE:0,05 mg
- Protein/Peptid-Typ:Rekombinant
- Spezies:Mouse
- Tag sequence:C-Fc tag
- Lagerbedingungen:Store at −20 °C, stable for 6 months after receipt. Please minimise freeze-thaw cycles.
- Endotoxingehalt:<0,1 ng/µg (1 IEU/µg) as determined by LAL test
- Proteinsynonym:Farp|ANGPTL4
- Protein/Peptid-Name:Angiopoietin like 4
- Purity:>95% as determined by reducing SDS-PAGE
- Molecular weight:54,6 kDa
- Sequence:Lys167-Ser410
- Zusammensetzung:Supplied as a 0,2 µm filtered solution of PBS, pH 7,4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the Lyophilised protein in ddH₂O. Please aliquot the reconstituted solution to minimise freeze-thaw cycles.
- Validierte Anwendungen:Bioassay
Spezifikationen
Über diesen Artikel
Angiopoietin-related protein 4（ANGPTL4）is a secreted protein and contains 1 fibrinogen C-terminal domain. The protein may act as a regulator of angiogenesis and modulate tumorigenesis. It inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 may exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity (By similarity). In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation.
- Fusion-Tag: C-Fc tag
This recombinant protein can be used for biological assays.