Robust polymer-based HILIC columns for positively charged analytes.

• Modified carboxyl group is suitable for cationic substance analysis including amines
• Best for aminoglycoside antibiotics, histamine/histidine, monoamine neurotransmitters and more
• The dominant separation mode is RP or IEX rather than HILIC mode
• Polymer-based packing material provides excellent chemical stability and minimum deterioration over an extended time period
• pH stability: 2 to 13 (silanol free)
• Easily regenerated by washing in an alkaline solution
• Also suitable for evaporative light scattering detector (ELSD), corona charged aerosol detector (CAD), and mass spectrometry (LC-MS/MS)

The HILICpak VC-50 column with carboxyl groups is a robust HILIC column for cationic substance analysis including amines. The polymeric base material polyvinyl alcohol offers great pH stability. The column housing is made of PEEK to reduce unwanted interaction.