Spezifikationen
- Antikörper-Typ:Primär
- Antigen-Name:MCM7/CDC47
- Klonalität:Polyklonal
- Konjugation:Alexa Fluor® 680
- Wirt:Rabbit
- ImmunoChemie:Yes
- ImmunFluoreszenz:Yes
- Isotyp:IgG
- Epitop:1-100/719
- Form:Liquid
- Gen-ID:4176
- Antigen-Synonyme:MCM 2|P1.1 MCM3|PNAS 146|Mcm7|P85MCM|Homolog of S. cerevisiae Cdc47|MCM 7|PNAS146|CDC 47|MCM7_HUMAN|P1.1-MCM3|P1CDC47|CDC47 homolog|MCM2|DNA replication licensing factor MCM7|CDC47|Minichromosome maintenance complex component 7|Minichromosome maintenance deficient 7|Minichromosome Maintainence 7|CDABP0042|MCM7 minichromosome maintenance deficient 7|Minichromosome maintenance protein 7
- Modification:Unmodified
- Lagerungspuffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:81 kDa
- Lagertemperatur:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Konzentration:1 µg/µl
- Transporttemperatur:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human CDC47
- Validierte Anwendungen:ICC
- Reinigung:Purified by Protein A
- Packung:Vial
- VE:100 µl
Spezifikationen
Über diesen Artikel
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumour suppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Type: Primary
Antigen: MCM7/CDC47
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 1-100/719
Host: Rabbit
Isotype: IgG
Reactivity: