Specifications
- Antikörper-Typ:Primär
- Antigen-Name:CD22/BLCAM
- Klonalität:Polyklonal
- Konjugation:Unconjugated
- ELISA:Yes
- Wirt:Rabbit
- ImmunoChemie:Yes
- ImmunFluoreszenz:Yes
- Isotyp:IgG
- Reaktivität:Human,Rat
- Epitop:701-847/847
- Form:Liquid
- Gen-ID:933
- Antigen-Synonyme:B-lymphocyte cell adhesion molecule|B-cell receptor CD22|Sialic acid-binding Ig-like lectin 2|BL-CAM|SIGLEC-2|CD22|SIGLEC2|T-cell surface antigen Leu-14
- Modification:Unmodified
- Lagerungspuffer:0,01 M TBS(pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:91 kDa
- Lagertemperatur:Shipped at 4 °C. Store at –20 °C for one year. Avoid repeated freeze/thaw cycles.
- Konzentration:1 µg/µl
- Transporttemperatur:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human CD22
- Validierte Anwendungen:ICC
- Reinigung:Purified by Protein A
- Packung:Vial
- VE:100 µl
Specifications
About this item
Mediates B-cell B-cell interactions. May be involved in the localisation of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
Type: Primary
Antigen: CD22/BLCAM
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Public Immunogen Range: 701-847/847
Host: Rabbit
Isotype: IgG
Reactivity: Human, Rat