Anti-NFKBIA/IKB alpha Rabbit Polyclonal Antibody (Alexa Fluor® 750)
BOSSBS-1287R-A750
: Bioss
- Antikörper-Typ:Primär
- Antigen-Name:NFKBIA/IKB alpha
- Klonalität:Polyklonal
- Konjugation:Alexa Fluor® 750
- Durchflusszytometrie:Yes
- Wirt:Rabbit
- ImmunoChemie:Yes
- ImmunFluoreszenz:Yes
- Isotyp:IgG
- Reaktivität:Chicken,Human,Bovine,Rat,Mouse
- Western blot:Yes
- Epitop:1-120/314
- Form:Liquid
- Gen-ID:18035
- Antigen-Synonyme:Nfkbia|AI46215|IkappaBalpha|IkB-alpha|Nfkbi|Ikba|NF-kappa-B inhibitor alpha|I-kappa-B-alpha
- Modification:Unmodified
- Lagerungspuffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:36 kDa
- Lagertemperatur:Store at –20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Konzentration:1 µg/µl
- Transporttemperatur:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from mouse IKB alpha
- Validierte Anwendungen:ICC
- Reinigung:Purified by Protein A
- Packung:Vial
- VE:100 µl
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localisation signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
Type: Primary
Antigen: NFKBIA/IKB alpha
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 1-120/314
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat, Bovine, Chicken