- Antikörper-Typ:Primär
- Antigen-Name:LONP1
- Klonalität:Polyklonal
- Konjugation:Alexa Fluor® 750
- Wirt:Rabbit
- ImmunoChemie:Yes
- ImmunFluoreszenz:Yes
- Isotyp:IgG
- Reaktivität:Human,Rat,Mouse
- Western blot:Yes
- Epitop:361-460/959
- Form:Liquid
- Gen-ID:9361
- Antigen-Synonyme:Mitochondrial ATP-dependent protease Lon|Lon protease homolog, mitochondrial|hLON|LONP|Lon protease-like protein|PRSS15|LON|Serine protease 15|LonHS|LONP1
- Modification:Unmodified
- Lagerungspuffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:98 kDa
- Lagertemperatur:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Konzentration:1 µg/µl
- Transporttemperatur:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human LONP1
- Validierte Anwendungen:ICC
- Reinigung:Purified by Protein A
- Packung:Vial
- VE:100 µl
ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand-specific manner. May regulate mitochondrial DNA replication and/or gene expression using site-specific, single-stranded DNA binding to target the degradation of regulatory proteins binding to adjacent sites in mitochondrial promoters. Endogenous substrates include mitochondrial steroidogenic acute regulatory (StAR) protein.
Type: Primary
Antigen: LONP1
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 361-460/959
Host: Rabbit
Isotype: IgG
Reactivity: Human; Mouse; Rat