1 mg

Unconjugated

Rekombinant

HEK293 cells

Human

His Tag (active trimer) (MALS verified)

–20 °C

Less than 1,0 EU per μg by the LAL method.

Anti-TNFSF11 (human IgG1) captured on CM5 chip via Anti-human IgG Fc antibodies surface can bind Human TNFSF11, His Tag (active trimer) (ACRBRAL-H5240) with an affinity constant of 0,274 nM as determined in a SPR assay (Biacore T200) (Routinely tested). Captured Human RANK, Mouse IgG2a Fc Tag, low endotoxin (ACRBRAK-H5251) on CM5 chip via Anti-Mouse antibodies surface can bind Human TNFSF11, His Tag (active trimer) (ACRBRAL-H5240) with an affinity constant of 0,309 nM as determined in a SPR assay (Biacore T200) (Routinely tested). Loaded Human RANK, Mouse IgG2a Fc Tag, low endotoxin (ACRBRAK-H5251) on AMC Biosensor, can bind Human TNFSF11, His Tag (active trimer) (ACRBRAL-H5240) with an affinity constant of 0.409 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested). Loaded Anti-TNFSF11 MAb (human IgG1) on AHC Biosensor, can bind Human TNFSF11, His Tag (active trimer) (ACRBRAL-H5240) with an affinity constant of 0.239 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

AAC51762.1

OPGL|ODF|TRANCE|CD254|RANKL

TNFSF11

>90% as determined by SDS-PAGE.

22,4 kDa

Low

Lyophilised from 0,22 μm filtered solution in PBS, pH 7,4. Normally trehalose is added as protectant before lyophilisation.

RT