Unconjugated

Rekombinant

HEK293 cells

Human

His Tag

–20 °C

Less than 1,0 EU per μg by the LAL method

Measured by its binding ability in a functional ELISA. Immobilised Human Siglec-15, His Tag (Cat. No. SG5-H52H3) at 5 μg/ml (100 μl/well) can bind Mouse Human chimeric MAb (5G12, Human IgG1) with a linear range of 0,3 - 2 ng/ml (QC tested). Measured by its binding ability in a functional ELISA. Immobilised Human Siglec-15, His Tag (Cat. No. SG5-H52H3) at 10 μg/ml (100 μl/well) on Nickel Coated plate, can bind Neu5Ac(a2-6)GalNAc-PAA-biotin with a linear range of 0.078-5 μg/ml (Routinely tested). Loaded Mouse Human chimeric MAb (5G12, Human IgG1) on AHC Biosensor, can bind Human Siglec-15, His Tag (Cat. No. SG5-H52H3) with an affinity constant of 0,52 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

Q6ZMC9-1

Siglec-15|SIGLEC-15|Siglec15|CD33L3|CD33 antigen-like 3|sialic acid-binding Ig-like lectin 15

Siglec-15

>90% as determined by SDS-PAGE.

28,4 kDa

Low

Lyophilised from 0,22 μm filtered solution in 25 mM MES, 150 mM NaCl, pH 5,5. Normally trehalose is added as protectant before lyophilisation.

RT