Human Recombinant VEGF-121 (from E. coli)

Vascular endothelial growth factor-A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. VEGF-A is a mediator of vascular growth, vascular permeability, and plays a role in stimulating vasodilation via nitric oxide-dependent pathways. VEGF-A has several alternatively spliced isoforms, with one being VEGF-121. The VEGF-121 isoform is a secreted protein that acts on receptors VEGFR-1 and VEGFR-2 to modulate endothelial cell function.

High quality
Low endotoxin
Affordable

: This product is for research use only and is not for use in humans.

Konjugation:
Unconjugated
Protein-Funktion:
Cytokine
Protein/Peptid-Typ:
Rekombinant
Ursprung:
E. coli
Spezies:
Human
Lagerbedingungen:
–20 °C
Endotoxingehalt:
Endotoxin LAL (EU/µg) ≤0,1
Biologische Aktivität:
Bioactivity Assay: HUVEC proliferation, ED₅₀ ≤5 ng/ml, Bioactivity ≥2,0×10⁵ units/mg
Gen-ID:
P15692-9
Reconstitution instructions:
Sterile water at 0,1 mg/ml
Frei von Endotoxinen:
N
Frei von Trägern:
Y
Frei von Proteasen:
N
Tierfrei:
Y
Proteinsynonym:
glioma-derived endothelial cell mitogen|VEGF-A|VPF
Protein/Peptid-Name:
VEGF-121 (AF)
Purity:
≥95%
Molecular weight:
14,2/28,4 kDa
Sequence:
MAPMAEGGGQ NHHEVVKFMD VYQRSYCHPI ETLVDIFQEY PDEIEYIFKP SCVPLMRCGG CCNDEGLECV PTEESNITMQ IMRIKPHQGQ HIGEMSFLQH NKCECRPKKD RARQEKCDKP RR
Endotoxinspiegel:
Low
Zusammensetzung:
0,1% Trifluoroacetic acid (TFA)
Frei von Nukleasen:
N
Sorte:
RUO
Transporttemperatur:
RT
Validierte Anwendungen:
Bioassay