Human Recombinant IL-6 (Animal free) (from E. coli)

Supplier: Shenandoah Biotechnology

Certificates

Supplier: Shenandoah Biotechnology

About this item

Interleukin 6 (IL-6) is an important pro-inflammatory and anti-inflammatory cytokine expressed by T cells, macrophages, and muscle cells. IL-6 signals through a receptor complex containing two receptors, IL-6Rα and gp130.

High quality
Low endotoxin
Affordable

IL-6 has an important function in promoting fever and can serve to stimulate an immune response to trauma. IL-6 is often used for growth of hybridoma cell lines. Human IL-6 is active on mouse and rat cells.

These research grade recombinant proteins are typically used as cytokines, growth factors and chemokines in cell based assays and cell culture.

Delivery: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.

Caution: For research use only.

Specifications

Konjugation:
Unconjugated
Protein-Funktion:
Cytokine
Protein/Peptid-Typ:
Rekombinant
Ursprung:
E. coli
Spezies:
Human
Lagerbedingungen:
−20 °C
Endotoxingehalt:
Endotoxin LAL (EU/µg) ≤1
Biologische Aktivität:
Bioactivity assay: B9 cell proliferation, ED50 ≤0,025 ng/ml, bioactivity ≥4,0×10⁷ units/mg
Gen-ID:
P05231
Reconstitution instructions:
Sterile water at 0,1 mg/ml
Frei von Endotoxinen:
N
Frei von Trägern:
Y
Frei von Proteasen:
N
Tierfrei:
Y
Proteinsynonym:
IFN-β2|HSF|BSF-2|B-cell differentiation factor|MGI-2
UniProtKB:
P05231
Protein/Peptid-Name:
IL-6
Purity:
≥97%
Molecular weight:
21 kDa
Sequence:
MPVPPGEDSK DVAAPHRQPL TSSERIDKQI RYILDGISAL RKETCNKSNM CESSKEALAE NNLNLPKMAE KDGCFQSGFN EETCLVKIIT GLLEFEVYLE YLQNRFESSE EQARAVQMST KVLIQFLQKK AKNLDAITTP DPTTNASLLT KLQAQNQWLQ DMTTHLILRS FKEFLQSSLR ALRQM
Endotoxinspiegel:
Low
Zusammensetzung:
10 mM sodium phosphate, pH 7,5
Frei von Nukleasen:
N
Sorte:
RUO
Transporttemperatur:
RT
Validierte Anwendungen:
Bioassay