Über diesen Artikel
Vascular endothelial growth factor-A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. VEGF-A is a mediator of vascular growth, vascular permeability, and plays a role in stimulating vasodilation via nitric oxide-dependent pathways. VEGF-A has several alternatively spliced isoforms, with VEGF-165 being the most abundant. The VEGF-165 isoform is a secreted protein that acts on receptors VEGFR-1 and VEGFR-2 to modulate endothelial cell proliferation and angiogenesis.
- High quality
- Low endotoxin
- Affordable
Animal-free proteins are ideal for researchers concerned about the ever-present risk of contaminating human proteins or trace growth factors from FBS and animal-derived ingredients typically used in standard recombinant protein production techniques.
Spezifikationen
- Konjugation:Unconjugated
- Protein-Funktion:Cytokine
- Protein/Peptid-Typ:Rekombinant
- Ursprung:E. coli
- Spezies:Dog
- Lagerbedingungen:−20 °C
- Endotoxingehalt:Endotoxin LAL (EU/µg) ≤0.1
- Biologische Aktivität:Bioactivity assay: TF-1 cell proliferation, ED50 ≤15 ng/ml, bioactivity ≥6,7×10⁴ units/mg
- Gen-ID:P48749
- Reconstitution instructions:Sterile water at 0,1 mg/ml
- Frei von Endotoxinen:N
- Frei von Trägern:Y
- Frei von Proteasen:N
- Tierfrei:Y
- Proteinsynonym:MGI-1GM|CSF-2|Pluripoietin-α
- UniProtKB:P48749
- Protein/Peptid-Name:GM-CSF
- Purity:≥95%
- Molecular weight:14,4 kDa
- Sequence:MAPTRSPTLV TRPSQHVDAI QEALSLLNNS NDVTAVMNKA VKVVSEVFDP EGPTCLETRL QLYKEGLQGS LTSLKNPLTM MANHYKQHCP PTPESPCATQ NINFKSFKEN LKDFLFNIPF DCWKPVKK
- Endotoxinspiegel:Low
- Zusammensetzung:10 mM sodium phosphate, pH 7,5
- Frei von Nukleasen:N
- Sorte:RUO
- Transporttemperatur:RT
- Validierte Anwendungen:Bioassay