Über diesen Artikel
Leukemia inhibitory factor (LIF) is a member of the interleukin 6 (IL-6) family that is made by a variety of adult and embryonic tissues. LIF signals through the glycoprotein 130 (gp130)/LIF receptor (LIFR) heterodimer to activate STAT3 and MAPK signaling. LIF functions during hematopoietic differentiation, neuronal cell differentiation, kidney development, and inflammatory processes. Human LIF may also be an important factor during human embryonic stem cell (hESC) self-renewal, pluripotency, and embryonic implantation.
- High Quality
- Low Endotoxin
- Affordable
A COA is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions. This product is for research use only and is not for use in humans.
Spezifikationen
- Konjugation:Unconjugated
- Protein-Funktion:Cytokine
- Protein/Peptid-Typ:Rekombinant
- Ursprung:HEK293 cells
- Spezies:Human
- Lagerbedingungen:–20 °C
- Endotoxingehalt:Endotoxin LAL (EU/µg) ≤0,1
- Biologische Aktivität:Bioactivity assay: TF-1 cell proliferation, ED50 ≤0,2 ng/ml, Bioactivity ≥5,0×10⁶ units/mg
- Gen-ID:P15018
- Reconstitution instructions:Sterile 10 mM acetic acid at 0.1 mg/ml
- Frei von Endotoxinen:N
- Frei von Trägern:Y
- Frei von Proteasen:N
- Tierfrei:Y
- Proteinsynonym:Leukocyte Inhibitory Factor
- Protein/Peptid-Name:LIF
- Purity:≥95%
- Molecular weight:19,8 kDa
- Sequence:MSPLPITPVN ATCAIRHPCH NNLMNQIRSQ LAQLNGSANA LFILYYTAQG EPFPNNLDKL CGPNVTDFPP FHANGTEKAK LVELYRIVVY LGTSLGNITR DQKILNPSAL SLHSKLNATA DILRGLLSNV LCRLCSKYHV GHVDVTYGPD TSGKDVFQKK KLGCQLLGKY KQIIAVLAQA F
- Endotoxinspiegel:Low
- Zusammensetzung:0,1% Trifluoroacetic Acid (TFA)
- Frei von Nukleasen:N
- Sorte:RUO
- Transporttemperatur:Ice pack
- Validierte Anwendungen:Bioassay