XBridge BEH C18 sorbent can be used over an entire range of mobile phase pH (1 to 12). The trifunctionally bonded C18 ligand provides with a universal column for most HPLC separations and gives you the widest usable pH range, superior low pH stability, and ultra-low column bleed. The XBridge BEH C8 sorbent is less retentive compared to the XBridge BEH C18 sorbent.