Pig Recombinant IL-4 (from E. coli)

Über diesen Artikel

Interleukin 4 (IL-4) is an immunomodulatory cytokine that functions to induce naïve helper T cells to differentiate into type 2 T helper (Th2) cells. Th2 cells subsequently produce more IL-4 in a positive feedback loop. IL-4 also promotes immunoglobulin IgG to IgE isotype switching on B cells. IL-4 binds the IL-4Rα receptor to activate STAT6 signaling.

High quality
Low endotoxin
Affordable

Delivery: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.

Caution: For research use only.

Spezifikationen

Konjugation:
Unconjugated
Protein-Funktion:
Cytokine
Protein/Peptid-Typ:
Rekombinant
Ursprung:
E. coli
Spezies:
Pig
Lagerbedingungen:
−20 °C
Endotoxingehalt:
Endotoxin LAL (EU/µg) ≤0.1
Biologische Aktivität:
Bioactivity assay: TF-1 cell proliferation, ED50 ≤2 ng/ml, bioactivity ≥5,0×10⁵ units/mg
Gen-ID:
Q04745
Reconstitution instructions:
Sterile water at 0,1 mg/ml
Frei von Endotoxinen:
N
Frei von Trägern:
Y
Frei von Proteasen:
N
Tierfrei:
N
Proteinsynonym:
BCGF|B-cell stimulatory factor-1|BCDF|BSF-1
UniProtKB:
Q04745
Protein/Peptid-Name:
IL-4
Purity:
≥95%
Molecular weight:
12,7 kDa
Sequence:
MHKCDITLQE IIKTLNILTA RKNSCMELPV TDVFAAPENT TEKETFCRAS TVLRHIYRHH TCMKSLLSGL DRNLSSMANM TCSVHEAKKS TLKDFLERLK TIMKEKYSKC
Endotoxinspiegel:
Low
Zusammensetzung:
10 mM sodium phosphate, pH 7,5
Frei von Nukleasen:
N
Sorte:
RUO
Transporttemperatur:
RT
Validierte Anwendungen:
Bioassay