Human Recombinant TNFR-1 (from E. coli)

Tumor necrosis factor receptor type 1 (TNFR-1) is expressed in most tissues and is activated by soluble and membrane-bound tumor necrosis factor alpha (TNF-α). TNFR-1 activates NF-κB and MAPK pathways to induce inflammation, promote apoptotic cell death, inhibit tumorigenesis, and inhibit viral replication.

High quality
Low endotoxin
Affordable

: For research use only.

Konjugation:
Unconjugated
Protein-Funktion:
Cytokine
Protein/Peptid-Typ:
Rekombinant
Ursprung:
E. coli
Spezies:
Human
Lagerbedingungen:
–20 °C
Endotoxingehalt:
Endotoxin LAL (EU/µg) ≤1
Biologische Aktivität:
Bioactivity Assay: Neutralization of human TNF alpha induced L929 cell cytolysis, ED₅₀ ≤100 ng/ml, Bioactivity ≥1,0×10⁴ units/mg
Gen-ID:
P19438
Reconstitution instructions:
Sterile water at 0,1 mg/ml
Frei von Endotoxinen:
N
Frei von Trägern:
Y
Frei von Proteasen:
N
Tierfrei:
N
Proteinsynonym:
TNFRSF1A|TNFR55|CD120a|TNFAR
Protein/Peptid-Name:
TNFR-1
Purity:
≥95%
Molecular weight:
18,3 kDa
Sequence:
MDSVCPQGKY IHPQNNSICC TKCHKGTYLY NDCPGPGQDT DCRECESGSF TASENHLRHC LSCSKCRKEM GQVEISSCTV DRDTVCGCRKN QYRHYWSENL FQCFNCSLCL NGTVHLSCQE KQNTVCTCHA GFFLRENECV SCSNCKKSLE CTKLCLPQI EN
Endotoxinspiegel:
Low
Zusammensetzung:
10 mM Sodium phosphate, pH 7,5
Frei von Nukleasen:
N
Sorte:
RUO
Transporttemperatur:
RT
Validierte Anwendungen:
Bioassay