Human recombinant FGF-21 (from E. coli)
Lieferant: Shenandoah Biotechnology
Zertifikate
Über diesen Artikel
Fibroblast growth factor 21 (FGF21) is an endocrine hormone that regulates energy homeostasis and exerts cardioprotective functions during heart injury. FGF21 is expressed in the liver, pancreas, heart, and adipose tissues.
- Produced from genetically modified E. coli
- Monomeric protein, containing 182 amino acids
FGF21 signaling is activated through the FGFR1c receptor and ß-Klotho co-receptor. FGF21 is an important regulator of glucose uptake and reduces cell apoptosis under stress conditions.
Delivery: Certificate of Analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.
Caution: This product is for research use only and is not for use in humans.
Spezifikationen
- Konjugation:Unconjugated
- Protein-Funktion:Cytokine
- Protein/Peptid-Typ:Rekombinant
- Ursprung:E. coli
- Spezies:Human
- Lagerbedingungen:–20 °C
- Endotoxingehalt:Endotoxin LAL (EU/µg) ≤0,1
- Biologische Aktivität:Bioactivity assay: NIH-3T3 proliferation with β-klotho and heparin, ED50 ≤500 ng/ml, Bioactivity ≥2,0 ×10³ unit/mg
- Gen-ID:Q9NSA1
- Reconstitution instructions:Sterile water at 0.1 mg/ml
- Frei von Endotoxinen:N
- Frei von Trägern:Y
- Frei von Proteasen:N
- Tierfrei:N
- Proteinsynonym:FGFL
- Protein/Peptid-Name:FGF-21
- Purity:≥95%
- Molecular weight:19,5 kDa
- Sequence:MHPIPDSSPL LQFGGQVRQR YLYTDDAQQT EAHLEIREDG TVGGAADQSP ESLLQLKALK PGVIQILGVK TSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYQS EAHGLPLHLP GNKSPHRDPA PRGPARFLPL PGLPPALPEP PGILAPQPPD VGSSDPLSMV GPSQGRSPSY AS
- Endotoxinspiegel:Low
- Zusammensetzung:10 mM sodium phosphate, 100 mM sodium chloride, pH 7,5
- Frei von Nukleasen:N
- Sorte:RUO
- Transporttemperatur:RT
- Validierte Anwendungen:Bioassay
Spezifikationen
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