Human Recombinant GDF-5 (from E. coli)

Growth differentiation factor 5 (GDF-5) is a member of the bone morphogenetic protein (BMP) and transforming growth factor beta (TGF-β) families and functions to regulate cell proliferation and differentiation in embryonic and adult tissues. GDF-5 is expressed in the central nervous system and promotes the survival of dopaminergic neurons in animal models of Parkinson's disease. GDF-5 is also important during chondrogenesis and chondrocyte differentiation.

High quality
Low endotoxin
Affordable

: For research use only.

Konjugation:
Unconjugated
Protein-Funktion:
Cytokine
Protein/Peptid-Typ:
Rekombinant
Ursprung:
E. coli
Spezies:
Human
Lagerbedingungen:
–20 °C
Endotoxingehalt:
Endotoxin LAL (EU/µg) ≤0,1
Biologische Aktivität:
Bioactivity Assay: Alkaline phosphatase activity in ATDC5 cells, ED₅₀ ≤1200 ng/ml, Bioactivity ≥8,3×10² units/mg
Gen-ID:
P43026
Reconstitution instructions:
Sterile water at 0,1 mg/ml
Frei von Endotoxinen:
N
Frei von Trägern:
Y
Frei von Proteasen:
N
Tierfrei:
N
Proteinsynonym:
CDMP-1
Protein/Peptid-Name:
GDF-5
Purity:
≥95%
Molecular weight:
13,7/27,4 kDa
Sequence:
MAPLATRQGK RPSKNLKARC SRKALHVNFK DmgWDDWIIA PLEYEAFHCE GLCEFPLRSH LEPTNHAVIQ TLMNSMDPES TPPTCCVPTR LSPISILFIDSA NNVVYKQY EDMVVESCGC R
Endotoxinspiegel:
Low
Zusammensetzung:
0,1% Trifluoroacetic acid (TFA)
Frei von Nukleasen:
N
Sorte:
RUO
Transporttemperatur:
RT
Validierte Anwendungen:
Bioassay