Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a member of the tumor necrosis factor (TNF) family of cytokines. TRAIL is widely produced by a variety of cell types including tumor cells, smooth muscle of the lung and spleen, cerebellar glial cells, and thyroid follicular cells. TRAIL is a cytotoxic protein that induces apoptosis in tumor cells through the activation of the death receptors DR4 and DR5. TRAIL also binds the neutralizing decoy receptors, DcR1 and DcR2. Human TRAIL is active on mouse cells.
- High Quality
- Low Endotoxin
- Affordable
A COA is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions. This product is for research use only and is not for use in humans.
- Konjugation:Unconjugated
- Protein-Funktion:Cytokine
- Protein/Peptid-Typ:Rekombinant
- Ursprung:E. coli
- Spezies:Human
- Lagerbedingungen:–20 °C
- Endotoxingehalt:Endotoxin LAL (EU/µg) ≤0,1
- Biologische Aktivität:Bioactivity: No biological activity data is available at this time
- Gen-ID:P50591
- Reconstitution instructions:Sterile water at 0.1 mg/ml
- Frei von Endotoxinen:N
- Frei von Trägern:Y
- Frei von Proteasen:N
- Tierfrei:N
- Proteinsynonym:Apo-2L|Apo-2 Ligand|CD253|TL2|TNFSF10
- Protein/Peptid-Name:TRAIL
- Purity:≥90%
- Molecular weight:19,5 kDa
- Sequence:MRERGPQRVA AHITGTRGRS NTLSSPNSKN EKALGRKINS WESSRSGHSF LSNLHLRNGE LVIHEKGFYY IYSQTYFRFQ EEIKENTKND KQMVQYIYKY TSYPDPILLM KSARNSCWSK DAEYGLYSIY QGGIFELKEN DRIFVSVTNE HLIDMDHEAS FFGAFLVG
- Endotoxinspiegel:Low
- Zusammensetzung:10 mM sodium phosphate, 50 mM sodium chloride, pH 7,5
- Frei von Nukleasen:N
- Sorte:RUO
- Transporttemperatur:RT