Human Recombinant GDNF (from E. coli)

Glial cell-derived neurotrophic factor (GDNF) is a neurotrophic factor that signals through a multicomponent receptor system to activate receptor tyrosine kinase RET signaling. GDNF promotes dopamine uptake, prevents motor neuron apoptosis, and supports the survival and differentiation of neurons.

High quality
Low endotoxin
Affordable

: For research use only.

Konjugation:
Unconjugated
Protein-Funktion:
Cytokine
Protein/Peptid-Typ:
Rekombinant
Ursprung:
E. coli
Spezies:
Human
Lagerbedingungen:
–20 °C
Endotoxingehalt:
Endotoxin LAL (EU/µg) ≤0,1
Biologische Aktivität:
Bioactivity Assay: C₆ proliferation, ED₅₀ ≤3 µg/ml, Bioactivity ≥3,3×10² units/mg
Gen-ID:
P39905
Reconstitution instructions:
Sterile water at 0,1 mg/ml
Frei von Endotoxinen:
N
Frei von Trägern:
Y
Frei von Proteasen:
N
Tierfrei:
N
Proteinsynonym:
ATF-1
Protein/Peptid-Name:
GDNF
Purity:
≥95%
Molecular weight:
15,2/30,4 kDa
Sequence:
MSPDKQMAVL PRRERNRQAA AANPENSRGK GRRGQRGKNR GCVLTAIHLN VTDLGLGYET KEELIFRYCS GSCDAAETTY DKILKNLSRN RRLVSDKVGQ ACCRPIAFDD DLSFLDDNLV YHILRKHSAK RCGCI
Endotoxinspiegel:
Low
Zusammensetzung:
10 mM Sodium citrate, 100 mM Sodium chloride, pH 4,0
Frei von Nukleasen:
N
Sorte:
RUO
Transporttemperatur:
RT
Validierte Anwendungen:
Bioassay