Human recombinant Sentrin-specific protease 2 (from E. coli)
PRSI92-222
:
- VE:50 µG
- Enzym-Typ:Rekombinant
- Ursprung:E. coli
- Spezies:Human
- Tag sequence:N-6 His, SUMO tag
- Lagerbedingungen:Store at −20 °C, stable for 6 months after receipt. Please minimize freeze−thaw cycles.
- Enzymname:Sentrin-specific Protease 2
- Purity:>95% as determined by reducing SDS-PAGE
- Molecular weight:39.2 kD
- Sequence:Asp363-Leu589
- Zusammensetzung:Supplied as a 0.2 µm filtered solution of 50 mM HEPES, 5% glycerol pH 7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH₂O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Validierte Anwendungen:Biological assays
SENP2 is an enzyme that belongs to the peptidase C48 family. SENP2 is a protease that catalyses two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SUMO1 is a small ubiquitin-like protein that can be covalently conjugated to other proteins. It has been implicated as a down-regulator of CTNNB1 levels and may therefore be a modulator of the Wnt pathway.
Fusion-Tag: N-6 His, SUMO tag
This recombinant protein can be used for biological assays. For research use only.