Mouse recombinant IL-6 non-lytic (from CHO cells)
Catalog # PRSI90-486
Supplier: ProSci Inc.
CAS Number:
Specifications
- VE:50 µG
- Protein/Peptid-Typ:Rekombinant
- Ursprung:CHO cells
- Spezies:Mouse
- Tag sequence:Fc Tag
- Lagerbedingungen:Stable for at least 1 year after receipt when stored at −20 °C. Working aliquots are stable for up to 3 months when stored at −20 °C.
- Biologische Aktivität:Shows the biological function of the IL-6 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain.
- Proteinsynonym:Interleukin-6|B Cell Hybridoma Growth Factor|Interleukin HP-1
- Protein/Peptid-Name:IL-6 non-lytic
- Purity:>98% (SDS-PAGE)
- Sequence:1-211
- Zusammensetzung:Lyophilized from 0.2um-filtered solution in PBS.
Specifications
About this item
Interleukin 6 (IL-6) is a pleiotropic alpha-helical cytokine that plays important roles in acute phase reactions, inflammation, hematopoiesis, bone metabolism and cancer progression. IL-6 activity is essential for the transition from acute inflammation to either acquired immunity or chronic inflammatory disease. It is secreted by multiple cell types as a 22kDa-28kDa phosphorylated and variably glycosylated molecule. IL-6 induces signallling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6R) and a signal transducing subunit (gp130). IL-6 is a key factor for the growth of plasma cells.
Fusion-Tag: Fc Tag
This recombinant proteins is for research use only.