Spezifikationen

VE:
50 µG
Protein/Peptid-Typ:
Rekombinant
Ursprung:
Cells
Spezies:
Human
Tag sequence:
C-6 His tag
Lagerbedingungen:
Store at −20 °C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Proteinsynonym:
6-P2ase liver isozyme|PFKFB1|F6PK|6PF-2-K/Fru-2|6-phosphofructo-2-kinase/fructose-2|Fructose-2|PFK|6-bisphosphatase 1|6-bisphosphatase|FBPase 1|PFRX
Protein/Peptid-Name:
PFKFB1
Purity:
> 95% as determined by reducing SDS-PAGE
Molecular weight:
55.6 kD
Sequence:
Ser2-Tyr471
Zusammensetzung:
Supplied as a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Validierte Anwendungen:
Bioassay

Spezifikationen

Über diesen Artikel

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 is an enzyme that in humans is encoded by the PFKFB1 gene. The enzyme forms a homodimer that catalyses both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. It belongs to the phosphoglycerate mutase family. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis.

Fusion-Tag: C-6 His tag

This recombinant protein can be used for biological assays. For research use only.