Human recombinant UROIIIS (from E. coli)
PRSI91-248
:
- VE:50 µG
- Protein/Peptid-Typ:Rekombinant
- Ursprung:E. coli
- Spezies:Human
- Tag sequence:C-6 His tag
- Lagerbedingungen:Store at −20 °C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
- Proteinsynonym:UROIIIS|Hydroxymethylbilane Hydrolyase [Cyclizing]|UROS|Uroporphyrinogen-III Cosynthase|Uroporphyrinogen-III Synthase
- Protein/Peptid-Name:UROIIIS
- Purity:> 95% as determined by reducing SDS-PAGE
- Molecular weight:29.7 kD
- Sequence:Met1-Pro277
- Zusammensetzung:Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 100mM NaCl, 10% Glycerol, pH 8.0. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Validierte Anwendungen:Bioassay
Uroporphyrinogen-III Synthase is an enzyme which belongs to the uroporphyrinogen-III synthase family. Uroporphyrinogen-III Synthase is ubiquitous and it is involved in Porphyrin metabolism. Porphyrins act as cofactors for a multitude of enzymes that perform a variety of processes within the cell such as Methionine synthesis (Vitamin B12) or oxygen transport (Heme). Uroporphyrinogen-III Synthase can catalyze cyclization of the linear Tetrapyrrole, Hydroxymethylbilane, to the Macrocyclic Uroporphyrinogen III, the branch point for the various sub-pathways leading to the wide diversity of Porphyrins. Defects in Uroporphyrinogen-III Synthase are the cause of Congenital Erythropoietic Porphyria (CEP).
- This recombinant protein can be used for biological assays. For research use only.
Fusion-Tag: C-6 His tag