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Human recombinant Angiogenin (from E. coli)
Catalog # PRSI91-183
Supplier:  ProSci Inc.
CAS Number:  
Human recombinant Angiogenin (from E. coli)
Catalog # PRSI91-183
Supplier:  ProSci Inc.
CAS Number:  

Specifications

  • VE:
    50 µG
  • Protein/Peptid-Typ:
    Rekombinant
  • Ursprung:
    E. coli
  • Spezies:
    Human
  • Lagerbedingungen:
    Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
  • Proteinsynonym:
    Ribonuclease 5|RNASE5|Angiogenin|RNase 5|ANG
  • Protein/Peptid-Name:
    Angiogenin
  • Purity:
    > 95% as determined by reducing SDS-PAGE
  • Molecular weight:
    14.27 kD
  • Sequence:
    Gln25-Pro147
  • Zusammensetzung:
    Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
  • Validierte Anwendungen:
    Bioassay

Specifications

About this item

Angiogenin belongs to the pancreatic ribonuclease family. Angiogenin is primarily expressed in the liver. It may act as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. Angiogenin is a potent stimulator of new blood vessel formation. And Angiogenin is endocytosed and translocated to the nucleus by binding to actin on the surface of endothelial cells. Angiogenic activity is regulated by interaction with RNH1 in vivo. In addition, Angiogenin is associated with susceptibility to amyotrophic lateral sclerosis, which is a degenerative disorder of motor neurons in the cortex, brain stem and spinal cord.

  • This recombinant protein can be used for biological assays. For research use only.