Spezifikationen
- Antikörper-Typ:Primär
- Antigen-Name:CD33 molecule
- Antigen-Symbol:CD33
- Klonalität:Polyklonal
- Konjugation:FITC (Fluorescein Isothiocyanate)
- Wirt:Rabbit
- ImmunoChemie:Yes
- Isotyp:IgG
- Reaktivität:Human
- Kreuzadsorption:No
- Form:liquid
- Gen-ID:945
- Antigen-Synonyme:SIGLEC-3|SIGLEC3|CD33|Siglec-3|Myeloid cell surface antigen CD33|Sialic acid-binding Ig-like lectin 3|p67
- Lagerungspuffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Lagertemperatur:Store at 4°C for 12 months
- Konzentration:1 μg/μl
- Transporttemperatur:4°C
- Immunogen:285-335/364
- Reinigung:Purified by Protein A
- VE:100 µl
Spezifikationen
Über diesen Artikel
Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: CD33
Clonality: Polyclonal
Clone: 0
Conjugation: FITC (Fluorescein Isothiocyanate)
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: