Spezifikationen
- Antikörper-Typ:Primär
- Antigen-Name:CutC Copper Transporter
- Antigen-Symbol:CUTC
- Klonalität:Polyklonal
- Konjugation:FITC (Fluorescein Isothiocyanate)
- Wirt:Rabbit
- ImmunoChemie:Yes
- Isotyp:IgG
- Reaktivität:Human,Rat,Mouse
- Kreuzadsorption:No
- Form:liquid
- Gen-ID:51076
- Antigen-Synonyme:CutC copper transporter homolog E. coli|CGI 32|CUTC_HUMAN|Copper homeostasis protein cutC homolog|CGI32|cutC|RP11-483F11.3.
- Lagerungspuffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Lagertemperatur:Store at 4°C for 12 months
- Konzentration:1 μg/μl
- Transporttemperatur:4°C
- Reinigung:Purified by Protein A
- VE:100 µl
Spezifikationen
Über diesen Artikel
Copper is an essential micronutrient used as a co-factor for several essential enzymes in all living organisms. Due to the high toxicity of copper, its metabolism is tightly regulated and defects in this regulation can cause Menkes (deficiency) or Wilson (accumulation) disease in various tissue. CUTC (cutC copper transporter homolog (E. coli)), also known as CGI-32, is a 273 amino acid protein belonging to the cutC family. CUTC is involved in copper homeostasis and is encoded by a gene located on human chromosome 10, which contains over 800 genes and 135 million nucleotides. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. Other chromosome 10 associated disorders include Cockayne syndrome, tetrahydrobiopterin deficiency and trisomy 10.
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: CUTC
Clonality: Polyclonal
Clone:
Conjugation: FITC (Fluorescein Isothiocyanate)
Epitope:
Host: Rabbit
Isotype:
Reactivity: