Specifications

• Antikörper-Typ:
  Primär
• Antigen-Name:
  Zic Family member 1
• Antigen-Symbol:
  ZIC1
• Klonalität:
  Monoklonal
• Klon:
  2D3
• Konjugation:
  Unconjugated
• ELISA:
  Yes
• Wirt:
  Mouse
• Reaktivität:
  Human
• Western blot:
  Yes
• Kreuzadsorption:
  No
• Gen-ID:
  7545
• Antigen-Synonyme:
  Zic1 encodes a zinc finger protein expressed in the developing or matured central nervous system in a highly restricted manner. Zic is expressed in granule cells that make synaptic contact with Purkinje cells. Zic1 is a gene critical to cerebellar pattern formation. The expression of Zic genes is first detected at gastrulation and at neurulation|becoming restricted to the dorsal neural ectoderm and the dorsal paraxial mesoderm. The Zic1 gene has been mapped to chromosome 9 in mouse. The 5' flanking region of the Zic1 gene contains a region-specific enhancer determined to be essential in in-vivo and in-vitro deletion analysis. The temporal profile of mRNA expression differs for each of the Zic gene products. The Drosophila odd-paired gene is highly homologous to the Zic gene family. Zic2 and Zic3 are highly similar genes. Zic2 is essential for the formation of the brain and Zic-3 is important for right and left axis formation.
• Lagertemperatur:
  Cool
• Transporttemperatur:
  Ice
• Größe:
  100 µg
• VE:
  100 µg