Ihre Suche nach: Proteine und Peptide

Supplier: Shenandoah Biotechnology

Cytokines for mouse neuronal cell culture. Neural Stem Cells (NSC) are self-renewing cells, of the neural lineage, capable of generating neurons (GABA, dopamine and motor neurons), astrocytes and oligodenrocytes. NSCs are marked by expression of Nestin and can be derived from fetal neural stem cells, adult neural stem cells, embryonic stem cells and adult somatic cells.

Supplier: Shenandoah Biotechnology

Cytokines for cell culture of mouse glioma cells. A glioma is a generic term used to describe tumors that arise from the glia tissue of the brain that supports and surrounds neurons. Glioma tumor cells can be successfully cultured ex vivo with EGF, FGF-basic (or FGF-2), and PDGFs (AA and BB).

Supplier: Shenandoah Biotechnology

IL-6 is an important pro-inflammatory and anti-inflammatory cytokine expressed by T cells, macrophages, and muscle cells. Signals through a receptor complex containing two receptors, IL-6Rα and gp130. Plays an important function in promoting fever and can serve to stimulate an immune response to trauma.

Supplier: Shenandoah Biotechnology

FLT-3 Ligand is a growth factor that regulates proliferation of early hematopoietic cells. FLT-3 Ligand binds to cells expressing the tyrosine kinase receptor FLT-3. FLT-3 ligand by itself does not stimulate proliferation of early hematopoietic cells, but synergizes with other CSFs and interleukins to induce growth and differentiation. Unlike SCF, FLT-3 ligand exerts no activity on mast cells. Multiple isoforms of FLT-3 Ligand have been identified.

Supplier: Shenandoah Biotechnology

Cytokines for polarizing T cells into T regulatory cells. T regulatory cells (Tregs) are a subset of T cells that suppress immune function. They are characterized by the expression of CD4, CD25 and Foxp3 and are known to produce immunosuppressive cytokines TGF-β 1 and IL-10. Tregs can be cultured from naive CD4+ T cells by culturing them in the presence of IL-2 and TGF-β 1 with CD3 and CD28 stimulation. In some cases cells are also cultured with neutralizing antibodies to IL-4, IFNγ and IL-12 and/or retinoic acid.

Supplier: Shenandoah Biotechnology

Cytokines for polarizing mouse T cells into Th17 cells. T helper 17 cells (Th17) are a distinct type of T cell subset that are thought to be important in immunity against microbes at the epitilial and mucosal interfaces of the body. Disruption of the regular function or balance of Th17 cells is thought to be involved in several autoimmune diseases and/or opportunistic infections. Th17 cells are characterized by their ability to produce IL-17, IL-22 and IL-21. Th17 cells can be cultured from naive CD4+ T cells by culturing them in the presence of anti-CD3 and anti-CD28 stimulation with recombinant IL-6 and recombinant TGF-β 1.

Supplier: ProSci Inc.

LCN2 is iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. LCN2 binds iron through association with 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin, and delivers or removes iron from the cell, depending on the context. LCN2 is involved in apoptosis due to interleukin-3 (IL3) deprivation: iron-loaded form increases intracellular iron concentration without promoting apoptosis, while iron-free form decreases intracellular iron levels, inducing expression of the proapoptotic protein BCL2L11/BIM, resulting in apoptosis. LCN2 is involved in innate immunity, possibly by sequestrating iron, leading to limit bacterial growth.

Supplier: OriGene

Purified recombinant protein of Homo sapiens sorting nexin 18 (SNX18), transcript variant 1.

Supplier: Shenandoah Biotechnology

SCF is a multipotent factor which affects cells of the myeloid, erythroid, mast, and lymphoid lineages.

Supplier: Apollo Scientific

L-Tyrosylglycine

Supplier: Apollo Scientific

Recombinant Protein G

Supplier: Apollo Scientific

Buserelin

Supplier: Apollo Scientific

Human Recombinant IL-2

Supplier: Apollo Scientific

Amastatin hydrochloride

Supplier: Apollo Scientific

Assay >10000 U/mg lyophilizedInhibitor of Trypsin, Chymotrypsin, Plasmin and otherproteolytic enzymes.

Supplier: Thermo Fisher Scientific

Glycylglycylglycine (Gly-Gly-Gly)

Supplier: ENZO LIFE SCIENCES

Bax inhibitor

Supplier: ENZO LIFE SCIENCES

From adenovirus type 40. Inactivated by 2 hours at 54°C.

Supplier: ENZO LIFE SCIENCES

Produced in E.coli.

Supplier: ENZO LIFE SCIENCES

Cathepsin substrate

Supplier: ENZO LIFE SCIENCES

Produced in CHO cells. The sequence coding for the 4 extracellular Ig-like domains of mouse LAG-3 (D1-D4) is fused to the Fc portion of mouse IgG2a (hinge-CH2-CH3).

Supplier: ENZO LIFE SCIENCES

Produced in E. coli. E. coli DnaJ is fused at the N-terminus to a His-tag.

Supplier: ENZO LIFE SCIENCES

Fluorogenic substrate for several matrix metalloproteinases (MMPs).

Supplier: ENZO LIFE SCIENCES

Produced in E. coli.

Supplier: ENZO LIFE SCIENCES

MAPKAPK substrate

Supplier: ENZO LIFE SCIENCES

Inhibitor of PP2A and calcineurin

Supplier: ENZO LIFE SCIENCES

Produced in E. coli.

Supplier: ENZO LIFE SCIENCES

Produced in E. coli.

Supplier: ENZO LIFE SCIENCES

Produced in E. coli. Human p62 (1-440 aa) is fused to a N-terminal GST-tag.

Supplier: ENZO LIFE SCIENCES

PTP substrate