You searched for: Proteine und Peptide

Proteine werden in Routine-Laborverfahren wie die Bindung von Enzymen oder Kopplung von Peptiden an Trägerproteine verwendet. Diese Sets, Lösungen und Kollagen-Matrizen erfüllen im Labor unzählige Funktionen, die für die Entwicklung von Beziehungen zwischen Proteinen und anderen zellulären Bestandteilen von Bedeutung sind. Die stimulierenden Proteine aus unserem Angebot besitzen verschiedene Aminosäuresequenzen und Funktionen, um die Proben so bearbeiten zu können, dass jegliche Untersuchungszwecke in jeglichen Bereichen erfüllt werden können.

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Recombinant HCV NS5a

Supplier: Biorbyt

Recombinant HCV NS5a

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HIV-1 p17/p24

Supplier: Biorbyt

HIV-1 p17/p24

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Recombinant HIV- M

Supplier: Biorbyt

Recombinant HIV- M

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HCV-N-G5

Supplier: Biorbyt

HCV-N-G5

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Recombinant TB ESAT

Supplier: Biorbyt

Recombinant TB ESAT

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Recombinant HBe Ag

Supplier: Biorbyt

Recombinant HBe Ag

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Human IL4 (from E. coli)

Supplier: Biorbyt

Human IL4 (from E. coli)

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HSV I Ag (from E. coli)

Supplier: Biorbyt

HSV I Ag (from E. coli)

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Human Recombinant TGF-beta 1 (Cell Culture Ready)

Supplier: STEMCELL Technologies

Conveniently and consistently add transforming growth factor beta 1 (TGF-ꞵ1) to your cultures with this cell culture-ready formulation. This human recombinant TGF-ꞵ1 is precisely reconstituted to 0,1 mg/ml in 100 mM acetic acid and requires no additional preparation, improving reproducibility. Endotoxin levels are verified, using the LAL method to ensure consistency for use across multiple applications. A member of the TGF-β superfamily, TGF-β1 regulates diverse cellular phenotypes. TGF-β1 binds to serine-threonine kinase type I and II receptors and activates signal transduction through SMAD2/3 proteins.

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Human Recombinant IL-34, His tag

Supplier: STEMCELL Technologies

Interleukin 34 (IL-34) is well known for its ability to induce the formation of colony-forming unit macrophages in human bone marrow cell cultures (Foucher et al.; Wei et al.). This dimeric glycoprotein is a member of the short-chain helical hematopoietic cytokine family (Baghdadi et al.; Foucher et al.), and exists in two isoforms that differ by a single glutamine (Chen et al.; Foucher et al; Wei et al.). IL-34 interacts with M-CSF to trigger tyrosine phosphorylation of the receptor and ERK1/2 pathways. (Wang et al.; Wei et al.). It is expressed in many tissues (heart, brain, lung, liver, kidney, thymus, testes, ovary, small intestine, prostate, and colon), with the highest expression in the spleen. In combination with RANKL, IL-34 induces osteoclast differentiation (Chen et al.; Foucher et al.). IL-34 expression is decreased in Alzheimer’s disease and atopic dermatitis, while high levels of IL-34 are found in many types of cancer correlated with poor prognosis, chronic heart failure or coronary artery disease, inflammatory bowel disease, influenza A infection, during acute liver transplant rejection or in non-alcoholic fatty liver disease, and with rheumatoid arthritis (Baghdadi et al.). It is therefore a possible pharmacological target for treating bone or inflammatory diseases (Chen et al.). This protein contains a His-residue tag at the carboxyl end of the polypeptide chain, and the protein was purified as a homodimer consisting of 39 kDa monomers (Lin et al.).

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Human Amyloid-β (1-42) Peptide (Trifluoroacetate Salt)

Supplier: STEMCELL Technologies

Human amyloid-β (1 to 42) peptide is a neurotoxic peptide fragment that can oligomerize to form amyloid plaques, thus contributing to the onset of Alzheimer's disease (Paradis et al.; Teplow; Wolfe). These neurotoxic peptide fragments also modulate the expression of Bcl-2 and Bax in human neurons (Paradis et al.).