Pifithrin-alpha hydrobromide
Pifithrin-α hydrobromide ≥98% (durch TLC)
Supplier: Enzo Life Sciences
Chemical inhibitor of p53 that protects mice from the side effects of cancer therapy. Reversibly blocks p53-dependent transcriptional activation and apoptosis. Protects against neuronal death in models of stroke and neurodegenerative disorders. Suppresses self-renewal of embryonic stem cells.
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Pifithrin-α hydrobromide ≥95%
Supplier: Apollo Scientific
Usage: Biochemical/life science applications.
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Pifithrin-α hydrobromide
Supplier: Abcam
p53 Inhibitor. Specifically blocks tumour supressor p53 transcriptional activity and can supress heat shock and glucocorticoid signalling pathways. Additionally offers protection to cells from p53 mediated apoptosis. Active in vivo; protects mice from chemotherapy side effects associated with p53 induction. Also aryl hydrocarbon receptor (AHR) agonist.
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